Protein Alignment trus and PDCD2L

DIOPT Version :9

• Sequence 1: NP_650205.1
• Gene: trus / 41540
• FlyBaseID: FBgn0038055
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_115722.1
• Gene: PDCD2L / 84306
• HGNCID: 28194
• Length: 358
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 133/500 - (26%)
• Similarity: 187/500 - (37%)
• Gaps: 165/500 - (33%)

  Fly     1 MAKNKSTVYLGYEDEEVTAKQEQLLNSCTNKIGGTPD-WPRHEVTIPSCPLCGAVRPLIVQMYAP 64
            ||.....|.||..|..|............:|:||.|| .|......|.|..||....|:||:|.|
Human     1 MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRPVCQRCGQPLALVVQVYCP 65

  Fly    65 LDRSQFHRSLYVFGCMNPVCSQ-NSKSWCCVRTQHLDHQYEVISEHSPKATPTKK-QNSKKKGKS 127
            |:.|.|||.|:||.|..|.||. .::||...|:|.|.             .|.:: |:::|:|.|
Human    66 LEGSPFHRLLHVFACACPGCSTGGARSWKVFRSQCLQ-------------VPEREAQDAQKQGNS 117

  Fly   128 SGLQAISWCSGADDWGDSSGGATEQAKTISVALDEAMDITADDDQNERNGNVRPNALQYAKSDIQ 192
              |.|..||.||||||..    ||:..:....||...|.::..|
Human   118 --LAAEDWCEGADDWGSD----TEEGPSPQFTLDFGNDASSAKD--------------------- 155

  Fly   193 IDEPAKLEQVKIAADDDDDEDESTSLENELISGFHQMDMISPQNADDDPNANCAAAAAPSLDGAG 257
            :|..|:|:.::              |::.::...|
Human   156 VDWTARLQDLR--------------LQDAVLGAAH------------------------------ 176

  Fly   258 ASAASAAIGAEIEGPETDLVLVDTPKKPERDLIALLKHTSGALSQIKDLTLKSYYIAVDVENKTQ 322
                                    |..|...|..                  .|||.|..|
Human   177 ------------------------PVPPGLPLFL------------------PYYICVADE---- 195

  Fly   323 AEEYENFGGALSMDHIRDLYQEYKLR-----DQNPGQS-PTGGASGPGEQGDENESYEKALPAHG 381
             ::|.:|   :::||...|.::|:.|     ||...|| |..|          :|.|||.:...|
Human   196 -DDYRDF---VNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDG----------DEKYEKTIIKSG 246

  Fly   382 DLVFHNFITTIHQNPGQLLRYSRDTIPL-LVAPFTE--PLPKCQNCRGETICEVQLLPTLIPKLR 443
            |..|:.|:..|.....|:||||....|| |..|.:|  .||.|..|.|:.|.|.||:|.|:..|:
Human   247 DQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSQCGGQRIFEFQLMPALVSMLK 311

  Fly   444 FQVNGCNAPIEFGNVLVFTCLKSCW----DTPDLMRYEHIVVQSE 484
            ....|.:  :|||.:||:||.||||    .||   ..|..::|.:
Human   312 SANLGLS--VEFGTILVYTCEKSCWPPNHQTP---MEEFCIIQED 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trus	NP_650205.1	PDCD2_C	371..482	CDD:282100	46/117 (39%)
PDCD2L	NP_115722.1	PDCD2_C	236..350	CDD:309358	46/118 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145839
Domainoid	1	1.000	84	1.000	Domainoid score	I8333
eggNOG	1	0.900	-	-		E1_KOG2061
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41861
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54449
OrthoDB	1	1.010	-	-		D1181470at2759
OrthoFinder	1	1.000	-	-		FOG0001596
OrthoInspector	1	1.000	-	-		oto90357
orthoMCL	1	0.900	-	-		OOG6_103161
Panther	1	1.100	-	-	LDO	PTHR46421
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1686
SonicParanoid	1	1.000	-	-		X4734
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.750