DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18549 and Mfsd11

DIOPT Version :9

Sequence 1:	NP_650203.3	Gene:	CG18549 / 41538	FlyBaseID:	FBgn0038053	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_848735.1	Gene:	Mfsd11 / 69900	MGIID:	1917150	Length:	449	Species:	Mus musculus

Alignment Length:	432	Identity:	189/432 - (43%)
Similarity:	279/432 - (64%)	Gaps:	17/432 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KFLMILILGFGFMFVFTAFQTMCNIEKTILDSISQEDDTFKGEGYTSLAIIYLFFSLSNWLAPSF 68
            |...|:|||..|||:||||||..|:.:|::.|::..|  |.|.|||||||||..||.||.:.||.
Mouse     7 KLFNIVILGVAFMFMFTAFQTCGNVAQTVIRSLNSTD--FHGSGYTSLAIIYGVFSASNLITPSV 69

  Fly    69 ISFTGPRVAMVVGALTYTAFMITFMFPSTVLLYVGSAVLGLGASITWTGQGTYLARCSESSTISR 133
            ::..||:::|.|..|.|:.::..|:.|.....|..|..:|:.|::.||.||..|...|:..||.|
Mouse    70 VAIVGPQISMFVSGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGR 134

  Fly   134 NSGVFWALLQCSMFIGNLFVYYQFQDKTRIDKETRNLVIGVLTVIAVLGIVFLAALR------FM 192
            |||:||||||.|:|.|||::|:.:|.||:|.:..|..|...||||:::|.|....:|      .:
Mouse   135 NSGIFWALLQSSLFFGNLYIYFAWQGKTQISEHDRRTVFIALTVISLVGTVLFFLIRKPDPENVL 199

  Fly   193 ADNAEHDNE----LEQKHTGCGQAIYALKSAGQLFLTKKMLLLSLAFFYTGLELSFFSGVFGSAI 253
            .:....|::    .|.......:|:.|.|.:.:|.:|::|||||:...||||||:|||||:|:.|
Mouse   200 GEEESCDDQDMEATESAQNNVTKAVDAFKKSLRLCVTREMLLLSVTTAYTGLELTFFSGVYGTCI 264

  Fly   254 GFTTKIAETPKEIVGLVGICIGAGEVFGGGLFGILGNKTTRYGRDPIVIAGYVMHMAAFFMTFIN 318
            |...|.....|.::||.||.||.||:.||.|||:| :|.:|:||:|:|:.|.::|..||::.|:|
Mouse   265 GAVNKFGTEEKSLIGLSGIFIGIGEILGGSLFGLL-SKNSRFGRNPVVLLGTLVHFVAFYLIFLN 328

  Fly   319 LPNSAPF---KDTTDISYLDPPRASIALVCAFLLGLGDACFNTQIYSMLGGEYVNNAVGAFALFK 380
            :|..||.   :.|..|:|:.|.: .:|::|:|||||||:|||||:.|:||..|..::..|||:||
Mouse   329 MPGDAPIAPVEGTNSIAYIRPSK-EVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAVFK 392

  Fly   381 FTQSVAAAISFFYSSHFGLYVQLGILVVMGTIGTIAFVFVEW 422
            |.||:.||::||||::..|:.||.::|:.|..|||:|..|||
Mouse   393 FVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFAVEW 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18549	NP_650203.3	MFS_MFSD11	8..423	CDD:340965	188/428 (44%)
Mfsd11	NP_848735.1	MFS_MFSD11	11..435	CDD:340965	188/428 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834964
Domainoid	1	1.000	217	1.000	Domainoid score	I2679
eggNOG	1	0.900	-	-		E1_KOG3098
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11517
Inparanoid	1	1.050	367	1.000	Inparanoid score	I2138
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54908
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002381
OrthoInspector	1	1.000	-	-		oto93684
orthoMCL	1	0.900	-	-		OOG6_103589
Panther	1	1.100	-	-	LDO	PTHR23294
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3864
SonicParanoid	1	1.000	-	-		X1405
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790