DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18549 and Mfsd11

DIOPT Version :9

Sequence 1:	NP_650203.3	Gene:	CG18549 / 41538	FlyBaseID:	FBgn0038053	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001101778.1	Gene:	Mfsd11 / 360667	RGDID:	1307394	Length:	450	Species:	Rattus norvegicus

Alignment Length:	437	Identity:	191/437 - (43%)
Similarity:	280/437 - (64%)	Gaps:	26/437 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KFLMILILGFGFMFVFTAFQTMCNIEKTILDSISQEDDTFKGEGYTSLAIIYLFFSLSNWLAPSF 68
            |...|:|||..|||:||||||..|:.:|::.|::..|  |.|.|||||||||..||.||.:.||.
  Rat     7 KLFNIVILGVAFMFMFTAFQTCGNVAQTVIRSLNSTD--FHGSGYTSLAIIYGVFSASNLITPSV 69

  Fly    69 ISFTGPRVAMVVGALTYTAFMITFMFPSTVLLYVGSAVLGLGASITWTGQGTYLARCSESSTISR 133
            ::..||:::|.|..|.|:.::..|:.|.....|..|..:|:.|::.||.||..|...|:..||.|
  Rat    70 VAIVGPQISMFVSGLFYSIYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGR 134

  Fly   134 NSGVFWALLQCSMFIGNLFVYYQFQDKTRIDKETRNLVIGVLTVIAVLGIVFLAALRFMADNAEH 198
            |||:||||||.|:|.|||::|:.:|.||:|.:..|..|...||||:::|.|    |.|:....:.
  Rat   135 NSGIFWALLQSSLFFGNLYIYFAWQGKTQISENDRRTVFIALTVISLVGTV----LFFLIRKPDP 195

  Fly   199 DNELEQKHTGCG---------------QAIYALKSAGQLFLTKKMLLLSLAFFYTGLELSFFSGV 248
            :|.|.::...|.               :|:.|.|.:.:|.:||:|||||:...||||||:|||||
  Rat   196 ENVLGEEDESCDDQDMEATESAQNNVTKAVDAFKKSLRLCVTKEMLLLSVTTAYTGLELTFFSGV 260

  Fly   249 FGSAIGFTTKIAETPKEIVGLVGICIGAGEVFGGGLFGILGNKTTRYGRDPIVIAGYVMHMAAFF 313
            :|:.||...|.....|.::||.||.||.||:.||.|||:| :|.:|:||:|:|:.|.::|..||:
  Rat   261 YGTCIGAVNKFGTEEKSLIGLSGIFIGIGEILGGSLFGLL-SKNSRFGRNPVVLLGTLVHFVAFY 324

  Fly   314 MTFINLPNSAPF---KDTTDISYLDPPRASIALVCAFLLGLGDACFNTQIYSMLGGEYVNNAVGA 375
            :.|:|:|..||.   :.|...:|:.|.: .:|::|:|||||||:|||||:.|:||..|..::..|
  Rat   325 LIFLNMPGDAPIAPVEGTNSSAYIRPSK-EVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPA 388

  Fly   376 FALFKFTQSVAAAISFFYSSHFGLYVQLGILVVMGTIGTIAFVFVEW 422
            ||:|||.||:.||::||||::..|:.||.::|:.|..|||:|..|||
  Rat   389 FAVFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFAVEW 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18549	NP_650203.3	MFS_MFSD11	8..423	CDD:340965	190/433 (44%)
Mfsd11	NP_001101778.1	UNC-93	14..166	CDD:114686	72/153 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338554
Domainoid	1	1.000	216	1.000	Domainoid score	I2628
eggNOG	1	0.900	-	-		E1_KOG3098
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11517
Inparanoid	1	1.050	366	1.000	Inparanoid score	I2100
OMA	1	1.010	-	-		QHG54908
OrthoDB	1	1.010	-	-		D338483at33208
OrthoFinder	1	1.000	-	-		FOG0002381
OrthoInspector	1	1.000	-	-		oto97227
orthoMCL	1	0.900	-	-		OOG6_103589
Panther	1	1.100	-	-	LDO	PTHR23294
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1405
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810