DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18549 and B0554.7

DIOPT Version :9

Sequence 1:	NP_650203.3	Gene:	CG18549 / 41538	FlyBaseID:	FBgn0038053	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001300037.1	Gene:	B0554.7 / 178566	WormBaseID:	WBGene00015260	Length:	473	Species:	Caenorhabditis elegans

Alignment Length:	469	Identity:	108/469 - (23%)
Similarity:	195/469 - (41%)	Gaps:	54/469 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FKFLMILILGFGFMFVFTAFQTMCNIEKTILDSISQED----DTFKGEGYTSLAIIYLFFSLSNW 63
            |:.|...:|||..:.:.|||.....|.::::.|:.:.:    |.:  .||...|:||..|..::.
Worm     8 FELLCAAMLGFAQLCMNTAFDAEAFILESVIHSVHEREPDRIDPY--AGYYGQAVIYGSFLTTSL 70

  Fly    64 LAPSFISFTGPRVAMVVGALTYTAFMITFMFPSTVLLYVGSAVLGLGASITWTGQGTYLARCSES 128
            ..||.::...|::.:|:.:..:.||...|:|.::...|..:.|||:|.:....|..|||...|..
Worm    71 FTPSLLNIWTPKILLVISSFCFAAFPFGFLFINSYYHYFSTVVLGVGKAFFNLGCTTYLTSHSTR 135

  Fly   129 STISRNSGVFWALLQCSMFIGNLFV-----------YYQFQDKTRI----------DKETRNLVI 172
            .:|..|..:.||:...|:.:|.:.:           :...::.|.|          |.|.|.|.:
Worm   136 RSIESNVSLQWAIGCGSLILGAMILGGMTWISEDRGFENLKNSTDIVEHSGGRVFDDFEIRLLSL 200

  Fly   173 GVLTVIAVLGIVFLAALRFMADNAEHDNELEQKHTGCGQAIYALKSAGQLFLTKKMLLLSLAFFY 237
             ||..:::|.::.:..|  .:::.|:..|..:|.   |..|..||......::.|:|.:......
Worm   201 -VLIAVSILAVIIVCLL--PSEDVENCIESSKKD---GSVIKTLKLTCSTLISPKILQIVPLCLL 259

  Fly   238 TGLELSFFSGVFGSAIGFTT---KIAETPKEIVGLVGICIGAGEVFGGGLFGILGNKTTRYGRDP 299
            .|...|.|..:..:::.|..   ::...|    .:.|:..|.|||..|.:...|..:...:|..|
Worm   260 CGFNASCFMSIIPTSMHFNQNNFRMTYIP----AVYGLGAGVGEVLMGMIVSELSKRIQGFGLKP 320

  Fly   300 IVIAGYVMHMAAFFMTFINLPNSAPFKDTTDIS---YLDPPRASIALVCAFLLGLGDACFNTQIY 361
            .::.|.|:......:...:.|..||.:.|:...   |...|   :..:.|||.|..|.|||....
Worm   321 TMVIGSVILTVYCALLHASTPMEAPMRPTSGEPIWFYQSYP---LIFLIAFLAGTSDCCFNGVRS 382

  Fly   362 SMLGGEYVNNAVGAFALFKFTQSVAAAISFFYSSHFGLYVQLGILVVMGTIGTIAFVFVEWGFKR 426
            .:......:....:|::.:..|:.|..|.||:|....||:....|.::....||.|..|.....:
Worm   383 VICALVMPSRRAQSFSVSRMYQAAACVIIFFFSPTIPLYIYTFGLPILAVCSTIVFFKVVNSTNK 447

  Fly   427 QHR--------EQE 432
            ..|        |||
Worm   448 MERKMTTETWLEQE 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18549	NP_650203.3	MFS_MFSD11	8..423	CDD:340965	102/445 (23%)
B0554.7	NP_001300037.1	UNC-93	16..172	CDD:114686	39/157 (25%)
B0554.7	NP_001300037.1	MFS_1	65..410	CDD:284993	77/357 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158412
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3098
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D338483at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23294
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810