DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Desat2 and scdb

DIOPT Version :9

Sequence 1:	NP_650201.1	Gene:	Desat2 / 41536	FlyBaseID:	FBgn0043043	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	XP_005156902.1	Gene:	scdb / 553734	ZFINID:	ZDB-GENE-050522-12	Length:	380	Species:	Danio rerio

Alignment Length:	314	Identity:	158/314 - (50%)
Similarity:	218/314 - (69%)	Gaps:	2/314 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DAQTVDGDLTTDRFQLKRAEKRRLPLVWRNIILFALVHLAALYGLHSIFTRAKLATTLFAAGLYI 88
            |..|...|:..|.:..|......:.:||||:||..|:||.||||: :|.......|.::....::
Zfish    67 DVTTTTEDVFDDSYVEKPGPSPPVQIVWRNVILMTLLHLGALYGM-TILPFVSSLTLIWTGVCFM 130

  Fly    89 IGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHRVHHKYSETDADPHNAT 153
            :..||:||||||||:||:|:|..|||:.|.:.|::|||:.:|.||||||||||:||||||||||.
Zfish   131 VSALGITAGAHRLWSHRSYRASLPLRIFLAVANSMAFQNDIYEWARDHRVHHKFSETDADPHNAR 195

  Fly   154 RGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMPLACFVLPTVIPMVYWN 218
            |||||:|:||||.:|||::.:|||.|...||:||.::||||:||.:.:.:.||::||::|..:|.
Zfish   196 RGFFFAHIGWLLVRKHPEVIDKGRKLTFEDLKADSVVMFQRRHYKLSVVVMCFLIPTLVPWFFWE 260

  Fly   219 ETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFVSAFTFGEGWHNYHHAF 283
            |:|.:::.|..:.|:...||.|||||||||.:|.||||..:||.:|.||:....|||:|||||.|
Zfish   261 ESLWTAYLVPCLLRYAVVLNATWLVNSAAHMWGMRPYDHNINPRENKFVAFSAIGEGFHNYHHTF 325

  Fly   284 PWDYKTAEWGCYSLNITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLRTGDGSHE 337
            |.||.|:|:|. .||:|.|||||...:|.|.|.:.|..:.|..||.|||||||:
Zfish   326 PHDYATSEFGS-RLNVTKAFIDLMCFLGLANDCRRVTHETILARVQRTGDGSHK 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat2	NP_650201.1	Delta9-FADS-like	76..317	CDD:239582	128/240 (53%)
Desat2	NP_650201.1	FA_desaturase	81..284	CDD:278890	109/202 (54%)
scdb	XP_005156902.1	Delta9-FADS-like	118..358	CDD:239582	128/240 (53%)
scdb	XP_005156902.1	FA_desaturase	122..326	CDD:278890	109/203 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	280	1.000	Domainoid score	I1638
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H74538
Inparanoid	1	1.050	359	1.000	Inparanoid score	I2172
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm6351
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	14.010