DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Desat2 and SPCC1281.06c

DIOPT Version :9

Sequence 1:	NP_650201.1	Gene:	Desat2 / 41536	FlyBaseID:	FBgn0043043	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_588170.1	Gene:	SPCC1281.06c / 2538753	PomBaseID:	SPCC1281.06c	Length:	479	Species:	Schizosaccharomyces pombe

Alignment Length:	337	Identity:	117/337 - (34%)
Similarity:	180/337 - (53%)	Gaps:	48/337 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 KRRLPLV--------------------------WRNI------ILFALVHLAALYGLHSIFTRAK 76
            ||.:|:|                          ||::      ::|.| .:.|:||:.:  |..:
pombe    26 KRTIPVVPSVPERKWDPKAPKHIQEQPWTMQNWWRHLNWLHCMLIFGL-PMIAIYGVFT--TPLQ 87

  Fly    77 LATTLFAAGLYIIGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHRVHHK 141
            ..|.:||...|....||:|||.||||:||.||||.||...|......||:.::..|:||||.||:
pombe    88 TKTLIFAIIYYAYSGLGITAGYHRLWSHRAYKAKKPLEYFLAAGGAAAFEGSIRWWSRDHRAHHR 152

  Fly   142 YSETDADPHNATRGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMPLACF 206
            |::||.||:|..:||:::||||::..::|  :..||. |:|||.:||.:||..:|:..:.....|
pombe   153 YTDTDKDPYNVKKGFWYAHVGWMIILQNP--RRIGRS-DVSDLNSDPFVMFNHRHFLPIASFMAF 214

  Fly   207 VLPTVIPMVYWNETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFVSAF- 270
            :.|::...:.|.: ....:|.|.:.|..|..:.|:.|||.||..|::|:|.| |..:|.|::|.
pombe   215 IFPSLFCGLLWGD-YRGGYFYAGVCRLVFVHHATFCVNSLAHLIGSQPFDDT-NSARNHFITALV 277

  Fly   271 TFGEGWHNYHHAFPWDYKTA-EWGCYSLNITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLRTGDG 334
            |.|||.||||||||.||:.. .|  |..:.|..||.:.:..|.||:|.|...:.||:.:::....
pombe   278 TLGEGNHNYHHAFPNDYRNGLRW--YEYDPTKIFIYIASLFGLAYNLNTFPDNEIQKGIVQQKQK 340

  Fly   335 SHELW----GWG 342
            ..:.|    .||
pombe   341 VLDRWRAKLNWG 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat2	NP_650201.1	Delta9-FADS-like	76..317	CDD:239582	98/242 (40%)
Desat2	NP_650201.1	FA_desaturase	81..284	CDD:278890	85/203 (42%)
SPCC1281.06c	NP_588170.1	OLE1	43..334	CDD:224316	110/300 (37%)
		FA_desaturase	91..304	CDD:278890	91/219 (42%)
		CYB5	345..474	CDD:227599	3/8 (38%)
		Cyt-b5	360..432	CDD:278597
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	180	1.000	Domainoid score	I809
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	207	1.000	Inparanoid score	I967
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		otm47019
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16
SonicParanoid	1	1.000	-	-		X207
TreeFam	1	0.960	-	-
	11	10.750