DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Desat2 and fat-5

DIOPT Version :9

Sequence 1:	NP_650201.1	Gene:	Desat2 / 41536	FlyBaseID:	FBgn0043043	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_507482.1	Gene:	fat-5 / 180162	WormBaseID:	WBGene00001397	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	309	Identity:	146/309 - (47%)
Similarity:	202/309 - (65%)	Gaps:	3/309 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QTVDGDLTTDRFQLKRAEKR--RLPLVWRNIILFALVHLAALYGLHSIFTRAKLATTLFAAGLYI 88
            |.:..||...|...:.::|:  ::.:||:|:.||..:|:.||.||:.:..:||.||..:...|:.
Worm    13 QFLAADLNEIRQMQEESKKQVIKMEIVWKNVALFVALHIGALVGLYQLVFQAKWATVGWVFLLHT 77

  Fly    89 IGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHRVHHKYSETDADPHNAT 153
            :|.:|||.|||||||||.|||....|:.|::.|:||||:.:..||||||.|||:::||||||:..
Worm    78 LGSMGVTGGAHRLWAHRAYKATLSWRVFLMLINSIAFQNDIIDWARDHRCHHKWTDTDADPHSTN 142

  Fly   154 RGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMPLACFVLPTVIPMVYWN 218
            ||.||:|:||||.|||..:|.:|..||||||..||:||||||:|..|:.:.||.|||.||:|.|.
Worm   143 RGMFFAHMGWLLVKKHDQLKIQGGKLDLSDLYEDPVLMFQRKNYLPLVGIFCFALPTFIPVVLWG 207

  Fly   219 ETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFVSAFTFGEGWHNYHHAF 283
            |:...:::.|.:||:||.|:.||.:||.:|..|.:|||...:...|.:.|....|||.|||||.|
Worm   208 ESAFIAFYTAALFRYCFTLHATWCINSVSHWVGWQPYDHQASSVDNLWTSIAAVGEGGHNYHHTF 272

  Fly   284 PWDYKTAEWGCYSLNITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLRTG 332
            |.||:|:|...: ||.|...||..|.||..||.||...:||||:..:.|
Worm   273 PQDYRTSEHAEF-LNWTRVLIDFGASIGMVYDRKTTPEEVIQRQCKKFG 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat2	NP_650201.1	Delta9-FADS-like	76..317	CDD:239582	123/240 (51%)
Desat2	NP_650201.1	FA_desaturase	81..284	CDD:278890	104/202 (51%)
fat-5	NP_507482.1	Delta9-FADS-like	65..305	CDD:239582	123/240 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163582
Domainoid	1	1.000	284	1.000	Domainoid score	I857
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I1385
Isobase	1	0.950	-	0.837287	Normalized mean entropy	S1208
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm4822
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.720