DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Desat2 and fat-7

DIOPT Version :9

Sequence 1:	NP_650201.1	Gene:	Desat2 / 41536	FlyBaseID:	FBgn0043043	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_504814.1	Gene:	fat-7 / 179100	WormBaseID:	WBGene00001399	Length:	338	Species:	Caenorhabditis elegans

Alignment Length:	332	Identity:	157/332 - (47%)
Similarity:	221/332 - (66%)	Gaps:	19/332 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DKSSRETGVLFEDDAQTVDGDLTTDRFQLKRAEKR---RLPLVWRNIILFALVHLAALYGLHSIF 72
            :|...::..||.|..:.:         |::...|:   ::.:||||:.|||.:|:||..||:.:.
Worm    14 EKDGLDSQYLFMDPNEVL---------QVQEESKKIPYKMEIVWRNVALFAALHVAAAIGLYELV 69

  Fly    73 TRAKLATTLFAAGLYIIGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHR 137
            ..||..|.:|:..||:....|:||||||||:|::|||..|:|:.|::.|.||.|:.:..||||||
Worm    70 FHAKWQTAVFSFALYVFSGFGITAGAHRLWSHKSYKATTPMRIFLMLLNNIALQNDIIEWARDHR 134

  Fly   138 VHHKYSETDADPHNATRGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMP 202
            .|||:::|||||||.||||||:|:||||.:|||.:||.|..||||||.:||:|:||||||:.|:.
Worm   135 CHHKWTDTDADPHNTTRGFFFTHMGWLLVRKHPQVKEHGGKLDLSDLFSDPVLVFQRKHYFPLVI 199

  Fly   203 LACFVLPTVIPMVYWNETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFV 267
            |.||:|||:||:.:|.||...:::||..||:||.|:.||.:|||||.||.:|||.:::..:|.|.
Worm   200 LFCFILPTIIPVYFWKETAFIAFYVAGTFRYCFTLHATWCINSAAHYFGWKPYDTSVSAVENVFT 264

  Fly   268 SAFTFGEGWHNYHHAFPWDYKTAEWGCYSL--NITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLR 330
            :....|||.||:||.||.||:.:|   |||  |.|...||..|.:|..||.||:|.:.|.|:|
Worm   265 TVVAVGEGGHNFHHTFPQDYRASE---YSLIYNWTRVLIDTAAVLGLVYDRKTIADEFISRQV-- 324

  Fly   331 TGDGSHE 337
            ...||.|
Worm   325 ANHGSEE 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat2	NP_650201.1	Delta9-FADS-like	76..317	CDD:239582	129/242 (53%)
Desat2	NP_650201.1	FA_desaturase	81..284	CDD:278890	111/202 (55%)
fat-7	NP_504814.1	Delta9-FADS-like	73..313	CDD:239582	129/242 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163578
Domainoid	1	1.000	284	1.000	Domainoid score	I857
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I1385
Isobase	1	0.950	-	0.837287	Normalized mean entropy	S1208
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm4822
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.720