DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Desat2 and Desat1

DIOPT Version :9

Sequence 1:	NP_650201.1	Gene:	Desat2 / 41536	FlyBaseID:	FBgn0043043	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_652731.1	Gene:	Desat1 / 117369	FlyBaseID:	FBgn0086687	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	245/343 - (71%)
Similarity:	285/343 - (83%)	Gaps:	0/343 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 TGVLFEDDAQTVDGDLTTDRFQLKRAEKRRLPLVWRNIILFALVHLAALYGLHSIFTRAKLATTL 81
            ||||||.|.:|.||.|..|...:|:||||||.|||||||.|..:|||||||.:.:.|.||..|.:
  Fly    38 TGVLFECDVETTDGGLVKDITVMKKAEKRRLKLVWRNIIAFGYLHLAALYGAYLMVTSAKWQTCI 102

  Fly    82 FAAGLYIIGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHRVHHKYSETD 146
            .|..||:|..||:|||||||||||:||||||||::||||||||||||.|||||||||||||||||
  Fly   103 LAYFLYVISGLGITAGAHRLWAHRSYKAKWPLRVILVIFNTIAFQDAAYHWARDHRVHHKYSETD 167

  Fly   147 ADPHNATRGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMPLACFVLPTV 211
            ||||||||||||||||||||||||::|.||:|:||||||||||||||:|:|.||||:|||::|||
  Fly   168 ADPHNATRGFFFSHVGWLLCKKHPEVKAKGKGVDLSDLRADPILMFQKKYYMILMPIACFIIPTV 232

  Fly   212 IPMVYWNETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFVSAFTFGEGW 276
            :||..|.|:..::|||||||||||.||:||||||||||||.|||||.:||::|..|:...|||||
  Fly   233 VPMYAWGESFMNAWFVATMFRWCFILNVTWLVNSAAHKFGGRPYDKFINPSENISVAILAFGEGW 297

  Fly   277 HNYHHAFPWDYKTAEWGCYSLNITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLRTGDGSHELWGW 341
            |||||.|||||||||:|.||||.||||||.|||||||||||||:.|:|::||.|||||:|..|||
  Fly   298 HNYHHVFPWDYKTAEFGKYSLNFTTAFIDFFAKIGWAYDLKTVSTDIIKKRVKRTGDGTHATWGW 362

  Fly   342 GDKDLTAEDARNVLLVDK 359
            ||.|...|:..:.::..|
  Fly   363 GDVDQPKEEIEDAVITHK 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat2	NP_650201.1	Delta9-FADS-like	76..317	CDD:239582	187/240 (78%)
Desat2	NP_650201.1	FA_desaturase	81..284	CDD:278890	156/202 (77%)
Desat1	NP_652731.1	Delta9-FADS-like	97..338	CDD:239582	187/240 (78%)
Desat1	NP_652731.1	FA_desaturase	98..305	CDD:278890	157/206 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464455
Domainoid	1	1.000	124	1.000	Domainoid score	I1803
eggNOG	1	0.900	-	-		E1_COG1398
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I1806
Isobase	1	0.950	-	0.837287	Normalized mean entropy	S1208
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm6351
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	P	PTHR11351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16
SonicParanoid	1	1.000	-	-		X207
	14	13.790