DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Srlp and Cdyl2

DIOPT Version :9

Sequence 1:	NP_650199.1	Gene:	Srlp / 41533	FlyBaseID:	FBgn0038049	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_083717.1	Gene:	Cdyl2 / 75796	MGIID:	1923046	Length:	503	Species:	Mus musculus

Alignment Length:	255	Identity:	64/255 - (25%)
Similarity:	110/255 - (43%)	Gaps:	52/255 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 KNILVEKDKNITLIGI-NRPQQRNAIDSLTASQLCDAFANFEADDTSPVAVLYGVGGSFCSGFD- 109
            ::|:|.|::..|.|.: ::....||:......::..|..|...|| |.:.:|..||..||||.|
Mouse   247 RDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDD-SKLLLLSAVGSVFCSGLDY 310

  Fly   110 ---ILEISTDEKEEISVDILMRPEGSVGPTRR-------QIKKPVVCGINGYCIANGLELALMCD 164
               |..:|:|.::|.:         .:....|       |.|||:|..|||..:..|..:..:||
Mouse   311 SYLIGRLSSDRRKEST---------RIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCD 366

  Fly   165 LRVMEESAVLGFFNRRFGVPMLDAGTIRL----------PAMIGLSRALDLILTGRPVGSQEAHD 219
            :....|.|       .|..|.   .||||          |.::|::.|.:::..||.:.:|||..
Mouse   367 IVWASEKA-------WFQTPY---ATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACS 421

  Fly   220 IGLVNRIV-PT---GTALGNALELATCLAKFPQRALIHDRNSVYSSTFETSTFHQAVQNE 275
            .|||:::. ||   ...:....|:|:|      .|::.:.:.....:|..|...:..:.|
Mouse   422 RGLVSQVFWPTTFSQEVMLRVKEMASC------SAVVLEESKCLVRSFLKSVLEEVNEKE 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srlp	NP_650199.1	crotonase-like	49..259	CDD:304874	61/235 (26%)
Cdyl2	NP_083717.1	CHROMO	7..55	CDD:214605
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..177
		crotonase-like	249..445	CDD:119339	57/215 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810