Protein Alignment Srlp and ECHDC1

DIOPT Version :10

• Sequence 1: NP_650199.1
• Gene: Srlp / 41533
• FlyBaseID: FBgn0038049
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001132982.1
• Gene: ECHDC1 / 55862
• HGNCID: 21489
• Length: 307
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 67/303 - (22%)
• Similarity: 132/303 - (43%)
• Gaps: 34/303 - (11%)

  Fly     9 LAQQVGQQARFTA--ASRT----------FSSTKALHKDPATQEAEAAPPKNILVEKDKN-ITLI 60
            |.|::.:....||  :.||          :|::...:::...:..:..|..:|.::|:.| |.::
Human     3 LKQEMAKSLLKTASLSGRTKLLHQTGLSLYSTSHGFYEEEVKKTLQQFPGGSIDLQKEDNGIGIL 67

  Fly    61 GINRPQQRNAIDSLTASQLCDAFANFEADDTSPVAVLYGVGGSFCSGFDILEISTDEKEEISVDI 125
            .:|.|.:.||...:...||.:.....|........::.|...:|.||.|:..:.:....|..:.:
Human    68 TLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAV 132

  Fly   126 LMRPEGSVGPTRRQIKKPV--VCGINGYCIANGLELALMCDLRVMEESAVLGFFNRRFGVPMLDA 188
            .|..:.::   .|.::.|:  |..:.|:.:..|.|....||.|:|...:.:.|.::..|:.....
Human   133 CMFMQNTL---TRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWG 194

  Fly   189 GTIRLPAMIGLSRALDLILTGRPVGSQEAHDIGLVNRIVPTGTALGNALELATCLAKFPQ----- 248
            ||.||..:||..:||.::.....:.|:.|.:||:|..::.:.....:..|....|.:|.|
Human   195 GTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFIQGPPEV 259

  Fly   249 -RALIHDRNSVYSSTFETSTFHQAVQNEVMFTSREIIEDMQNG 290
             |||   :.||.|.  ......:|:|||     |:::..:..|
Human   260 IRAL---KKSVCSG--RELYLEEALQNE-----RDLLGTVWGG 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srlp	NP_650199.1	crotonase-like	49..259	CDD:474030	51/218 (23%)
ECHDC1	NP_001132982.1	CaiD	61..300	CDD:440647	57/245 (23%)