DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Srlp and zgc:101569

DIOPT Version :9

Sequence 1:	NP_650199.1	Gene:	Srlp / 41533	FlyBaseID:	FBgn0038049	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001005995.2	Gene:	zgc:101569 / 449822	ZFINID:	ZDB-GENE-041010-72	Length:	309	Species:	Danio rerio

Alignment Length:	279	Identity:	124/279 - (44%)
Similarity:	177/279 - (63%)	Gaps:	25/279 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GQQARFTAASRTFSSTKALHKDPATQEAEAAPPKNILVEKDKNITLIGINRPQQRNAIDSLTASQ 78
            ||:...:.:::...:|.:....|...|...|            :.|||||||:.|||::..||.:
Zfish    26 GQRFNSSTSNKERKTTSSGSNGPVVSERRGA------------VMLIGINRPEARNAVNRETAQR 78

  Fly    79 LCDAFANFEADDTSPVAVLYGVGGSFCSGFDILEIS-TDEKEEISVDILMRPEGSVGPTRRQIKK 142
            |.:..:.|:.||:..|.|||||||:||:|||:.|:: ..:..|:..|:...| |.:||:|.::.|
Zfish    79 LTEELSAFDQDDSLNVTVLYGVGGNFCAGFDLKELAHGSDSLELEQDVSSGP-GPMGPSRMRLSK 142

  Fly   143 PVVCGINGYCIANGLELALMCDLRVMEESAVLGFFNRRFGVPMLDAGTIRLPAMIGLSRALDLIL 207
            |::..::||.:|.||||||:.|:||.|||:::|.|.||||||::|.||:|||.:|||||||||||
Zfish   143 PLIAAVSGYAVAGGLELALLADMRVAEESSIMGVFCRRFGVPLIDGGTVRLPQLIGLSRALDLIL 207

  Fly   208 TGRPVGSQEAHDIGLVNRIVPTGTALGNALELATCLAKFPQRALIHDRNSVYSSTFETSTFHQAV 272
            |||||.:.||...||.||:||.|.||..|||||..::.|||..|..||||.|.:.|::::|:||:
Zfish   208 TGRPVKAHEALAFGLANRVVPDGQALQEALELAEQVSAFPQLCLRADRNSAYHALFDSTSFNQAM 272

  Fly   273 QNEVMFTSREIIEDMQNGI 291
            |.|.           .|||
Zfish   273 QYET-----------DNGI 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srlp	NP_650199.1	crotonase-like	49..259	CDD:304874	108/210 (51%)
zgc:101569	NP_001005995.2	PRK08259	46..304	CDD:236205	121/259 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582208
Domainoid	1	1.000	217	1.000	Domainoid score	I2615
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44730
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3368
OMA	1	1.010	-	-		QHG56076
OrthoDB	1	1.010	-	-		D1234730at2759
OrthoFinder	1	1.000	-	-		FOG0009134
OrthoInspector	1	1.000	-	-		otm26451
orthoMCL	1	0.900	-	-		OOG6_108084
Panther	1	1.100	-	-	LDO	PTHR43802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5949
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770