DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Srlp and HIPP1

DIOPT Version :9

Sequence 1:	NP_650199.1	Gene:	Srlp / 41533	FlyBaseID:	FBgn0038049	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_649261.1	Gene:	HIPP1 / 40302	FlyBaseID:	FBgn0037027	Length:	926	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	74/381 - (19%)
Similarity:	120/381 - (31%)	Gaps:	125/381 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AASRTFSSTKALHKDPATQEAEAAPPKNILVEKDKNITLIGINRPQQRNAIDSLTAS----QLCD 81
            :|..|..||          :||..||.   |||.:.:.|       :..|:::|:.|    .|.:
  Fly     7 SAVTTLEST----------QAEEPPPG---VEKVETLEL-------KTAALETLSESAGPTDLEN 51

  Fly    82 AFANFEADDTSPVAVLYGVGGSFCSGFDILEISTDEKEEISVDILMRPEGSVGPTRRQIK---KP 143
            ..||....:..|             |.|  |:||.|:|...:..:..|:.:     .::|   .|
  Fly    52 ELANLNGSEEGP-------------GLD--ELSTLEREIAKLHNIRPPDAA-----SEVKDSDTP 96

  Fly   144 VVCGINGYCIANGLEL-----ALMCDLRVMEESAVLGFFNRRFGVPMLDAGTIRLPAMIGLSRAL 203
            :....||     |||.     ...|...::||........:....|:               ..:
  Fly    97 IALADNG-----GLEPRQAPDEAKCRTPIIEEGNAASGNGQSSESPL---------------EEV 141

  Fly   204 DLILTGRPVGSQEAHDIGLVNRIVPTGTALGNALELATCLAKFPQRALIHDRNSVYSSTFETSTF 268
            |||...:  |:..:||       .|||                .::..:....|......|....
  Fly   142 DLIALLK--GTDTSHD-------QPTG----------------EEKCTLEKALSELDGVGEDGDV 181

  Fly   269 HQAVQNEVMFTSREIIEDMQNGIKWFNQTFKPDTTHSWLKRDRSMADWDDEEVAEAAAQKEKLKQ 333
            ...::.|..|...||.:|....   .::...|....|...:..|:          .:..|.||..
  Fly   182 GVTIEGEGQFEIMEIDDDEGES---SSRKASPKVPASKPIKSNSL----------PSISKHKLSP 233

  Fly   334 EQEAALAEAEKQKQAEKAQKRSKKTEESAAESV-----------DSKDPKDKPNEK 378
            ||..|:|    .:|....:.:|::.|..|..||           |..|..|...:|
  Fly   234 EQARAVA----LEQMAGLKPKSRRKEPPAPPSVVAPIDIVSSLNDDWDDYDSEEDK 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srlp	NP_650199.1	crotonase-like	49..259	CDD:304874	40/221 (18%)
HIPP1	NP_649261.1	crotonase-like	673..870	CDD:119339
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451181
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740