DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Srlp and Mtpalpha

DIOPT Version :9

Sequence 1:	NP_650199.1	Gene:	Srlp / 41533	FlyBaseID:	FBgn0038049	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_609299.1	Gene:	Mtpalpha / 34276	FlyBaseID:	FBgn0028479	Length:	783	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	86/323 - (26%)
Similarity:	146/323 - (45%)	Gaps:	62/323 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GLLAQQVGQQARFTAA----SRTFSSTKALHKDPATQEAEAAPPKNILVEKDKNITLIGINRPQQ 67
            |.:::|...|.:.|.|    ::.....:.:..:||     ....|::..:....:.:|.|:.|..
  Fly    11 GQISRQQLLQNKCTRALPISAQLLQRRRLMSTNPA-----PVANKHLHTKVVNGVLVIKIDSPNA 70

  Fly    68 RNAIDSLTASQLCDAFANFEAD-DTSPV---AVLY-GVGGSFCSGFDI--LEISTDEKEEISVD- 124
            :  ::|| .|::.|.|.....| :|:|.   |||. |..|.|.:|.||  ||.....:|...:.
  Fly    71 K--VNSL-GSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADIGMLEACQTAEEATLISH 132

  Fly   125 ----ILMRPEGSVGPTRRQIKKPVVCGINGYCIANGLELALMCDLRVMEESAVLGFFNRRFGVP- 184
                :..|.|.|        |||:|..|:|.|:..||||||.|..|:..:.:     ..:.|:|
  Fly   133 GAQVMFDRMERS--------KKPIVAAISGVCLGGGLELALACHYRIATKDS-----KTKLGLPE 184

  Fly   185 -ML-----DAGTIRLPAMIGLSRALDLILTGRPVGSQEAHDIGLVNRIV-PTGTAL--------- 233
             ||     ..||:|||.:..:..|||:.|||:.|.:..|..:|:|:.:| |.|..|
  Fly   185 VMLGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIE 249

  Fly   234 ---GNALELATCLAKFPQRALIHDRNSVYS--STFETSTFHQAVQNEVMFTSREIIEDMQNGI 291
               ..|:::|..||....| :..:::.:.|  .:|...|  ..|:|::..|:|:.:....||:
  Fly   250 YLEKTAVQVANDLASGKLR-VNREKSGLVSKIQSFVMDT--DFVKNKIFDTARKQVLKASNGL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srlp	NP_650199.1	crotonase-like	49..259	CDD:304874	69/241 (29%)
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	81/296 (27%)
		crotonase-like	52..235	CDD:119339	61/198 (31%)
		3HCDH_N	375..553	CDD:280833
		3HCDH	556..651	CDD:279114
		3HCDH	689..768	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810