Protein Alignment Srlp and HADHA

DIOPT Version :10

• Sequence 1: NP_650199.1
• Gene: Srlp / 41533
• FlyBaseID: FBgn0038049
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_000173.2
• Gene: HADHA / 3030
• HGNCID: 4801
• Length: 763
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 87/331 - (26%)
• Similarity: 142/331 - (42%)
• Gaps: 75/331 - (22%)

  Fly    13 VGQQARFTA---------ASRTFSSTKAL----HKDPATQEAEAAPPKNILVEKDKNITLIGINR 64
            :|..:||:|         ..|.|:.:.||    |             .|..|:.|  :.::.||.
Human     7 IGILSRFSAFRILRSRGYICRNFTGSSALLTRTH-------------INYGVKGD--VAVVRINS 56

  Fly    65 PQQR-NAIDSLTASQLCDAFANFEADDTSPVAVLY-GVGGSFCSGFDILEIST----DEKEEISV 123
            |..: |.:.....|:..:......|.|....|||. ...|.|.:|.||..::.    .|..::|.
Human    57 PNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQ 121

  Fly   124 D---ILMRPEGSVGPTRRQIKKPVVCGINGYCIANGLELALMCDLRV--MEESAVLGFFNRRFGV 183
            :   |:.:.|.|.        ||:|..|||.|:..|||:|:.|..|:  .:...|||......|.
Human   122 EAQRIVEKLEKST--------KPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGA 178

  Fly   184 PMLDAGTIRLPAMIGLSRALDLILTGRPVGSQEAHDIGLVNRIV-PTGTAL--------GNALEL 239
            .....||.|||.|:|:..|||::||||.:.:..|..:|||:::| |.|..|        ....|:
Human   179 LPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEV 243

  Fly   240 ATCLAK-------FPQR--ALIHDRNSVYSST--FETSTFHQAVQNEVMFTSR-------EIIED 286
            |...||       .|:|  .|: ::.:.|:.|  |.....::.|:.:|...::       :||:.
Human   244 AITFAKGLADKKISPKRDKGLV-EKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDV 307

  Fly   287 MQNGIK 292
            ::.||:
Human   308 VKTGIE 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srlp	NP_650199.1	crotonase-like	49..259	CDD:474030	68/238 (29%)
HADHA	NP_000173.2	fa_ox_alpha_mit	27..762	CDD:131494	83/311 (27%)