Protein Alignment Srlp and ECI1

DIOPT Version :9

• Sequence 1: NP_650199.1
• Gene: Srlp / 41533
• FlyBaseID: FBgn0038049
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001910.2
• Gene: ECI1 / 1632
• HGNCID: 2703
• Length: 302
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 65/289 - (22%)
• Similarity: 108/289 - (37%)
• Gaps: 67/289 - (23%)

  Fly    47 KNILVEKD--KNITLIGINRPQQRNAIDSLTASQLCDAFANFE--ADDTS--PVAVLYGVGGSFC 105
            :.:|||.|  ..:.::....|    .::||:...|.:...:.|  .:|.|  .|.:.....|.|.
Human    45 QRVLVEPDAGAGVAVMKFKNP----PVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFS 105

  Fly   106 SGFDILEISTDEKEEIS------VDILMRPEGSVGPTRRQIKKPVVCGINGYCIANGLELALMCD 164
            :|.|:.|:........:      .::.:|        ..|....:|..|||.|.|.|..:||.||
Human   106 AGLDLTEMCGRSPAHYAGYWKAVQELWLR--------LYQSNLVLVSAINGACPAGGCLVALTCD 162

  Fly   165 LRVMEESA--VLGFFNRRFGV--PMLDAGTIRLPAMIG---LSRALDLILTGRPVGSQEAHDIGL 222
            .|::.::.  .:|....:.|:  |.....|  |...||   ..|||.|.|...|.   ||..:|:
Human   163 YRILADNPRYCIGLNETQLGIIAPFWLKDT--LENTIGHRAAERALQLGLLFPPA---EALQVGI 222

  Fly   223 VNRIVPTGTALGNALELATCLAKFPQRA---------------LIHDRNSVYSSTFETSTFHQAV 272
            |:::||.......||.........|..|               |:..|::             .|
Human   223 VDQVVPEEQVQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDA-------------DV 274

  Fly   273 QNEVMFTSREIIEDMQNGIKWFNQTFKPD 301
            ||.|.|.|::.|   |..::.:.:..|.:
Human   275 QNFVSFISKDSI---QKSLQMYLERLKEE 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srlp	NP_650199.1	crotonase-like	49..259	CDD:304874	56/243 (23%)
ECI1	NP_001910.2	ECH_1	52..298	CDD:306810	61/278 (22%)
		Substrate binding. /evidence=ECO:0000269|PubMed:15351645, ECO:0007744|PDB:1SG4	106..110		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810