DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aos1 and UBA4

DIOPT Version :9

Sequence 1:	NP_650198.1	Gene:	Aos1 / 41532	FlyBaseID:	FBgn0029512	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_011979.1	Gene:	UBA4 / 856511	SGDID:	S000001153	Length:	440	Species:	Saccharomyces cerevisiae

Alignment Length:	159	Identity:	36/159 - (22%)
Similarity:	69/159 - (43%)	Gaps:	8/159 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LTEAENELYDRQI---RLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVT 75
            |:..|.:.|.||:   ...|:..|.:|:..|:|:.|..|||......:..:||..:.::|:..|.
Yeast    39 LSLEEYQRYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVE 103

  Fly    76 EEDFCSQFLVPRESLNTNRAEASLTRARALNPMVDISADREPLKEKTSEFFGQF-DVVVVNGATN 139
            ..:...|.|.....:...:.|::......|||.:::..  .|::..:|..|..| ....:...|:
Yeast   104 TSNLHRQVLHDSSRVGMLKCESARQYITKLNPHINVVT--YPVRLNSSNAFDIFKGYNYILDCTD 166

  Fly   140 EELLR--IDTICRDLGVKFIATDVWGTFG 166
            ..|.|  :..:..:||:..::....||.|
Yeast   167 SPLTRYLVSDVAVNLGITVVSASGLGTEG 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aos1	NP_650198.1	Aos1_SUMO	19..>172	CDD:238769	34/154 (22%)
Aos1	NP_650198.1	ThiF	22..>167	CDD:279270	34/151 (23%)
UBA4	NP_011979.1	ThiF_MoeB_HesA_family	46..279	CDD:238386	34/152 (22%)
UBA4	NP_011979.1	RHOD_ThiF	316..440	CDD:238784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810