DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Aos1 and SAE1A

DIOPT Version :9

Sequence 1:	NP_650198.1	Gene:	Aos1 / 41532	FlyBaseID:	FBgn0029512	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_567712.1	Gene:	SAE1A / 828596	AraportID:	AT4G24940	Length:	322	Species:	Arabidopsis thaliana

Alignment Length:	337	Identity:	111/337 - (32%)
Similarity:	161/337 - (47%)	Gaps:	40/337 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ELTEAENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEE 77
            ||||.|..|||||||:||..:|:||..|.||::|:.|..||..|||:|:||.||.|:||:....|
plant     5 ELTEQETALYDRQIRVWGANAQRRLTKAHILVSGIKGTVAEFCKNIVLAGVGSVTLMDDRLANME 69

  Fly    78 DFCSQFLV-PRESLNTNR--AEASLTRARALNPMVDISADREPLKEKTSEFFGQFDVVVVNGATN 139
            ...:.||: |.|::.:.:  ||......:..||||.:|.::..|....::||.||||||:...:.
plant    70 ALNANFLIPPDENVYSGKTVAEICSDSLKDFNPMVRVSVEKGDLSMLGTDFFEQFDVVVIGYGSR 134

  Fly   140 EELLRIDTICRDL--GVKFIATDVWGTFGFYFASLQKHSYVEDVIKHKVVANSEKKKKYETVSIP 202
            .....::..||.|  .|.|...|...:.|..|..||.:.|.:..::..|..........|.:|:|
plant   135 ATKKYVNEKCRKLKKRVAFYTVDCRDSCGEIFVDLQDYKYTKKKLEEMVECELNFPSFQEAISVP 199

  Fly   203 TQRDVDYPGYSAWLDF-----DVTEPSYLRKLKRNGPGVLL-----LSVLQKFRTTHKRDPSYKT 257
            .:   ..|..:|.|.|     :|.|.|..||   :|...||     |.:.::....:....|:
plant   200 WK---PIPRRTAKLYFAMRVIEVFEESEGRK---HGECSLLDLARVLEIKKQLCEANSVSESH-- 256

  Fly   258 READLELLRGIRDELLPNSILGDEALGLIFAQISPAVAVVGGVVAQEVIKVVTKLEAPHRNLFVF 322
                      |.|.||...|.|.       .:..|..|:|||::||||||.|:....|.:|.|.:
plant   257 ----------IPDILLERLITGT-------TEFPPVCAIVGGILAQEVIKAVSGKGDPLKNFFYY 304

  Fly   323 DPETCAGYVEAI 334
            |.|...|.:|.|
plant   305 DGEDGKGVMEDI 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aos1	NP_650198.1	Aos1_SUMO	19..>172	CDD:238769	59/157 (38%)
Aos1	NP_650198.1	ThiF	22..>167	CDD:279270	56/149 (38%)
SAE1A	NP_567712.1	Aos1_SUMO	11..314	CDD:238769	104/327 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1641
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4019
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1692
OMA	1	1.010	-	-		QHG54790
OrthoDB	1	1.010	-	-		D1180926at2759
OrthoFinder	1	1.000	-	-		FOG0003336
OrthoInspector	1	1.000	-	-		otm3157
orthoMCL	1	0.900	-	-		OOG6_102966
Panther	1	1.100	-	-	LDO	PTHR10953
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2228
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840