Protein Alignment Aos1 and UBA7

DIOPT Version :9

• Sequence 1: NP_650198.1
• Gene: Aos1 / 41532
• FlyBaseID: FBgn0029512
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_003326.2
• Gene: UBA7 / 7318
• HGNCID: 12471
• Length: 1012
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 115/432 - (26%)
• Similarity: 173/432 - (40%)
• Gaps: 108/432 - (25%)

  Fly     5 MDTSETAVELTEAENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLL 69
            ||..:.:..|.|   |||.||:.:.|..:.:|::.|::|::||.|||||:.||::|.||.|:.|.
Human     1 MDALDASKLLDE---ELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLH 62

  Fly    70 DDKDVTEEDFCSQFLVPRESLNTNRAEASLTRARALNPMVDISADREPLKEKTSEFFGQFDVVVV 134
            |.......|..:|||:..:.|..:|||||......||..|.:......:   |.:....|.|||:
Human    63 DPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVL 124

  Fly   135 NGATNEELLRIDTICRDLGVKFIATDVWGTFGFYFASLQKHSYVEDVIKHKVVANSEKKKKYETV 199
            ..|..||.|::.|:|...||.|:|.|..|..|..|....:...|:|..:.:.:..:.:.....:.
Human   125 TAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSP 189

  Fly   200 SIPTQRD------------VDYPGYSAWLDFDVTEP--------------------SYLR----- 227
            .|.|.|.            |.:.|....::.:..:|                    .|||
Human   190 GILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAIT 254

  Fly   228 KLKRN-------------GPGVLLLS---------------VLQKFRTTHKRDPS-YKTREA--- 260
            ::||.             .|.|:..|               .|.||:..|.|.|. :...:|
Human   255 EVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETV 319

  Fly   261 -----DLELLRGIRDELLPNSILGDEALGLIFA-----QISPAVAVVGGVVAQEVIKVVTKLEAP 315
                 |||.|:...:|.|...:  ||||....|     .:||.||::|.|.||||:|.:::...|
Human   320 VGLARDLEPLKRTEEEPLEEPL--DEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMP 382

  Fly   316 HRNLFVFD--------------PETCA-------GYVEAIGA 336
            ......||              ||.||       |.:...||
Human   383 LDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGA 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aos1	NP_650198.1	Aos1_SUMO	19..>172	CDD:238769	56/152 (37%)
		ThiF	22..>167	CDD:279270	52/144 (36%)
UBA7	NP_003326.2	ThiF	10..1010	CDD:330201	113/423 (27%)
		2 approximate repeats	23..575		106/407 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810