Protein Alignment Aos1 and APP-BP1

DIOPT Version :9

• Sequence 1: NP_650198.1
• Gene: Aos1 / 41532
• FlyBaseID: FBgn0029512
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001261699.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 98/510 - (19%)
• Similarity: 155/510 - (30%)
• Gaps: 199/510 - (39%)

  Fly    13 ELTEAENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEE 77
            ||:: :::.|||||||||...|..|..|.:.:..:..:|.|..|.::|.|:....:.|...|.||
  Fly    10 ELSD-KSKKYDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEE 73

  Fly    78 DFCSQFLVPRESLNTNRAEASLTRARALNP-----MVDISADREPLKEKTSEFFGQFDVVVVNGA 137
            |..:.|.:....|..::|.|.:...:.|||     .||.|||.  |......||..||:|:.:..
  Fly    74 DLGNNFFLDSSYLGKSKALACMQLLQELNPDVNGDYVDESADF--LLANRPNFFDSFDLVIASNL 136

  Fly   138 TNEELLRIDTICRDLGVKFIATDVWGTFGFYFASLQKHSYVE----------------DVIK--- 183
            ..:.||.:.....:|.|..|.....|..|.....:::|..||                |.::
  Fly   137 NEQTLLLLAERLWELNVPLIYCRSLGMLGTIRLQIREHCIVEAHPDNRQFDLRLEHPFDALREHL 201

  Fly   184 ---------------HKVV-------------ANSEKKKKYETVSIPTQRDVDYPGYSA------ 214
                           ||.:             ..:.|:|.....:|..:...|...|..
  Fly   202 DGTEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKADEENYEEAIKAVN 266

  Fly   215 -------------------------------WL------DFDVTE-------PSYLRKLKRNGPG 235
                                           |:      .|.:.|       |..|..:..|...
  Fly   267 TAFGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKALKHFVIHENEGHLPLPGVLPDMTANTDS 331

  Fly   236 VLLLSVLQKFRTTHKRDPSY-KTRE------------------------ADLELLRGIR------ 269
            .:.|..:.:.:.....|..| |.:|                        |.|.::||.|
  Fly   332 YIALQHIYRQQALQDADQVYHKCQEYLKQLALPADSIDERSVRLICKEAAGLAVIRGTRIAEEYE 396

  Fly   270 --DELLP---------------------------------------------------------N 275
              ..|||                                                         :
  Fly   397 KSSRLLPLVEDNELQGNLTAYNFALRAYERFLSECGNIPGECIVEQDIGRLKSIAAKMLSDLGMH 461

  Fly   276 SILGDEALGLIF----AQISPAVAVVGGVVAQEVIKVVTKLEAPHRNLFVFDPET 326
            :.:.|:.|..|.    |::....|.:||..||||||::||...|..|.|:::..|
  Fly   462 ATISDDVLHEICRYGGAELHAVSAFIGGCAAQEVIKIITKQYKPIDNTFIYNAIT 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aos1	NP_650198.1	Aos1_SUMO	19..>172	CDD:238769	47/157 (30%)
		ThiF	22..>167	CDD:279270	46/149 (31%)
APP-BP1	NP_001261699.1	APPBP1_RUB	16..522	CDD:238770	96/503 (19%)
		ThiF	17..>171	CDD:223552	47/155 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10953
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1600
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870