DRSC/TRiP Functional Genomics Resources

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Protein Alignment Aos1 and Atg7

DIOPT Version :9

Sequence 1:NP_650198.1 Gene:Aos1 / 41532 FlyBaseID:FBgn0029512 Length:337 Species:Drosophila melanogaster
Sequence 2:NP_611350.1 Gene:Atg7 / 37141 FlyBaseID:FBgn0034366 Length:684 Species:Drosophila melanogaster


Alignment Length:333 Identity:75/333 - (22%)
Similarity:117/333 - (35%) Gaps:110/333 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 AENEL-YDRQIRLWGLESQKRLR---TAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEE 77
            |||.: .:.::..|.|.....|.   ..|.|:.|...||..:.:|::..|...:.|||...|   
  Fly   313 AENSVNLNLKLMKWRLVPDLNLEIISQTKCLLFGAGTLGCAVARNLLSWGFKHITLLDSGKV--- 374

  Fly    78 DFCSQFLVP-RESLNT-------NRAEASLT--RARALNP-------MVDISADREPLKEKTSEF 125
                .|..| |::|.|       ||.:|:..  |.:.:||       :::|......:.|.    
  Fly   375 ----GFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGES---- 431

  Fly   126 FGQFDVVVVNGATNEELLRIDTICRDLGVKFIATDV----W---------------GTFGFYFAS 171
                    :...|.|.|..|:.:.:|..|.|:.||.    |               ...||    
  Fly   432 --------LLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLPTLLGAAKEKIVINAALGF---- 484

  Fly   172 LQKHSYVEDVIKHKVVANSEKKKKYETVSIPTQRDVDYPGYSAWLDFDVTEPSYLRKLKR----- 231
               .||:  |::|   ..:.|:...:...|...:.::......:...|||.|....|.:.     
  Fly   485 ---DSYL--VMRH---GTTRKEAGDDGQEIEGLKCINGDQLGCYFCNDVTAPGNSLKDRTLDQQC 541

  Fly   232 --NGPGV----------LLLSVLQKFRTTHKRD---PSY----------KTREADLELLRGIRDE 271
              ..|||          ||:::||     |.|.   |:|          :|.|...|.|.||   
  Fly   542 TVTRPGVSNIAASYAVELLVALLQ-----HPRKELAPAYYAQSGRGRSEETEEKVPEGLLGI--- 598

  Fly   272 LLPNSILG 279
             ||:||.|
  Fly   599 -LPHSIRG 605

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Aos1NP_650198.1 Aos1_SUMO 19..>172 CDD:238769 40/192 (21%)
ThiF 22..>167 CDD:279270 37/183 (20%)
Atg7NP_611350.1 ATG7_N 9..303 CDD:293029
E1_like_apg7 11..682 CDD:273590 75/333 (23%)
Apg7 341..658 CDD:238763 69/305 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446848
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0476
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10953
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.930

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