DRSC/TRiP Functional Genomics Resources

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Protein Alignment Aos1 and Uba5

DIOPT Version :9

Sequence 1:NP_650198.1 Gene:Aos1 / 41532 FlyBaseID:FBgn0029512 Length:337 Species:Drosophila melanogaster
Sequence 2:NP_572722.2 Gene:Uba5 / 32094 FlyBaseID:FBgn0030305 Length:404 Species:Drosophila melanogaster


Alignment Length:363 Identity:73/363 - (20%)
Similarity:120/363 - (33%) Gaps:104/363 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 LESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEEDFCSQFLVPRESLNTNRA 95
            ::..:|:|...:.|.|:.|:|:.....:...|:..:.|.|...|...:....|..| :....::.
  Fly    65 VKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTP-DQAGLSKV 128

  Fly    96 EASLTRARALNPMVDISADREPLKEKTSEFFGQF---------------DVVVVNGATNEELLRI 145
            .|:......:||.|:|......:  .|.|.|.:|               |:|:......|..:.|
  Fly   129 AAAAATLSFINPDVEIETHNYNI--TTVENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAI 191

  Fly   146 DTICRDLGVKFIATD-----VWGTFGFY-------FASLQKHSYVEDVIKHKVVANSEKKKKYET 198
            :..|.:..:.:..:.     |.|...|.       ||........|::        .||..|.|.
  Fly   192 NAACNERNLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVAENI--------DEKTLKREG 248

  Fly   199 V---SIPTQRDV--------------------DYPGYSAWLDFDVTEPSYLRKLK-----RNGPG 235
            |   |:||...:                    ||.||:|..||   .|....|..     ||   
  Fly   249 VCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLGYNALSDF---FPKMTLKPNPQCDDRN--- 307

  Fly   236 VLLLSVLQK-FRTTHK----------RDPSYKTREADLELLRGIRDELLPNS--------ILGDE 281
               ..|.|| |:...|          .:|.:.|.|..:||:.    |..|.|        ::|: 
  Fly   308 ---CLVRQKEFQARPKPVLIEEKAVSEEPLHATNEWGIELVA----EDAPESNTTPAETPVMGE- 364

  Fly   282 ALGLIFAQISPAVAVVGGVVAQEVIKVVTKLEAPHRNL 319
              ||..|..:|..:   ...::|.:...|..|....:|
  Fly   365 --GLRLAYEAPEKS---SETSEETVSAATADETSLEDL 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Aos1NP_650198.1 Aos1_SUMO 19..>172 CDD:238769 31/167 (19%)
ThiF 22..>167 CDD:279270 28/155 (18%)
Uba5NP_572722.2 ThiF_MoeB_HesA_family 52..297 CDD:238386 48/245 (20%)
ThiF 53..310 CDD:279270 51/264 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446836
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0476
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10953
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.930

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