DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aos1 and Uba2

DIOPT Version :9

Sequence 1:	NP_650198.1	Gene:	Aos1 / 41532	FlyBaseID:	FBgn0029512	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001094049.1	Gene:	Uba2 / 308508	RGDID:	1312023	Length:	639	Species:	Rattus norvegicus

Alignment Length:	176	Identity:	45/176 - (25%)
Similarity:	80/176 - (45%)	Gaps:	27/176 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 KILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEEDFCSQFLVPRESLNTNRAEASLTRARAL 105
            ::|:.|..|:|.|:.||::|:|.:.:.|:|...:...:...|||..::.:..::|:.:.......
  Rat    19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQF 83

  Fly   106 NPMVDISADREPL--KEKTSEFFGQFDVVVVNGATNEELL-RIDTICRDLGVKFIATDVWGTFGF 167
            :|..:|.|..:.:  .:...|||.|| ::|:|...|.... .::.:|....|..|.:   ||.|
  Rat    84 HPQANIEAHHDSIMNPDYNVEFFRQF-ILVMNALDNRAARNHVNRMCLAADVPLIES---GTAG- 143

  Fly   168 YFASLQKHSYVEDV--IKHKVVANSEKKKKYETVSIPTQRDVDYPG 211
                     |:..|  ||..|.      :.||....||||  .:||
  Rat   144 ---------YLGQVTTIKKGVT------ECYECHPKPTQR--TFPG 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aos1	NP_650198.1	Aos1_SUMO	19..>172	CDD:238769	32/133 (24%)
Aos1	NP_650198.1	ThiF	22..>167	CDD:279270	31/128 (24%)
Uba2	NP_001094049.1	ThiF	9..>175	CDD:279270	45/176 (26%)
		Uba2_SUMO	19..443	CDD:238766	45/176 (26%)
		UAE_UbL	451..537	CDD:291402
		UBA2_C	548..634	CDD:292812
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900