DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aos1 and Uba7

DIOPT Version :9

Sequence 1:	NP_650198.1	Gene:	Aos1 / 41532	FlyBaseID:	FBgn0029512	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001380849.1	Gene:	Uba7 / 301000	RGDID:	1308323	Length:	990	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	106/384 - (27%)
Similarity:	158/384 - (41%)	Gaps:	78/384 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ENELYDRQIRLWGLESQKRLRTAKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEEDFCSQ 82
            :.|||.||:.:.||.:.:|:|.||:|:.||.|||||:.||::|.||.|:.|.|.......|..:|
  Rat     2 DEELYSRQLYVLGLPAMQRIREAKVLLCGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQ 66

  Fly    83 FLVPRESLNTNRAEASLTRARALNPMVDISADREPLKEKTSEFFGQFDVVVVNGATNEELLRIDT 147
            |.:..|||..:|||||..:...||..|.||..|..:   |.:....|.|||:..:..|:.|.:..
  Rat    67 FFLSEESLGRSRAEASQPQLAQLNEAVQISVHRGDI---TEDLVRGFQVVVLTDSKLEDQLNMGA 128

  Fly   148 ICRDLGVKFIATDVWGTFGFYF-------------------ASLQKHS----------------- 176
            :|....|.|:..:..|..|..|                   |::|..|
  Rat   129 LCHKNRVYFLMAETRGLVGRLFCDFGEDFTVVDPTEVEPTSAAIQDISQGSPGIVTLRGGSKRPS 193

  Fly   177 -YVEDVIKHKVVANSEKKKKYETVSIPTQRD-----VDYPGYSAWLDFD-VTEPSYLRKLKRNGP 234
             |..|::....:....:...:....:..|:|     .|...:|.:|... |||....:.:|....
  Rat   194 FYDGDLVMFSDIEGMVELNSHSPQPVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVKHKPL 258

  Fly   235 GVLLLS----------------------VLQKFRTTHKRDPS-YKTREA--------DLELLRGI 268
            .:.||.                      .|.||:..|.|.|. :...:|        |||.|:|.
  Rat   259 DIALLQPCMVVQNTQEIQRAHCLHQTFHALHKFQQLHGRLPKPWDPDDAETVVWLAQDLEPLKGA 323

  Fly   269 RDELLPNSILGDEALGLIFAQISPAVAVVGGVVAQEVIKVVTKLEAPHRNLFVFDPETC 327
            ::|.|..::|...||... ..:||..|::|||.||||:|.|:....|......||...|
  Rat   324 KEESLDEALLRTIALSSA-GSLSPMAAILGGVAAQEVLKAVSGKFMPLDQWLYFDALEC 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aos1	NP_650198.1	Aos1_SUMO	19..>172	CDD:238769	58/171 (34%)
Aos1	NP_650198.1	ThiF	22..>167	CDD:279270	53/144 (37%)
Uba7	NP_001380849.1	Ube1	1..988	CDD:273603	106/384 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910