Protein Alignment Prosalpha2 and PRE5

DIOPT Version :10

• Sequence 1: NP_524328.1
• Gene: Prosalpha2 / 41531
• FlyBaseID: FBgn0086134
• Length: 234
• Species: Drosophila melanogaster
• Sequence 2: NP_014045.1
• Gene: PRE5 / 855362
• SGDID: S000004931
• Length: 234
• Species: Saccharomyces cerevisiae
• Alignment Length: 238
• Identity: 65/238 - (27%)
• Similarity: 115/238 - (48%)
• Gaps: 12/238 - (5%)

  Fly     1 MATERYSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPL--YEQHSVH 63
            |....|.....||||:|:|.|:||||.|:..|:.:||:.::...|:....::...|  |::..:.
Yeast     1 MFRNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQKKIIK 65

  Fly    64 RVEMIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVR 128
            ..|    |:|:..:|:.||.|:|....|:......|.:...:.|.:....:....|:.|||.|.|
Yeast    66 CDE----HMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGR 126

  Fly   129 PFGVSLLICGWDNDRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLEL----DDAVH 189
            |:||.|||.|:|....:|.:..|||.......||:|..:...||:||:.....:::    |:.:.
Yeast   127 PYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIK 191

  Fly   190 TAILTLKEGF-EGKMTADNIEIGICDQN-GFQRLDPASIKDYL 230
            ..:..:.:.. :..:|.||:.|.|..:: .|...|..::..|:
Yeast   192 AGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha2	NP_524328.1	proteasome_alpha_type_2	6..231	CDD:239719	64/233 (27%)
PRE5	NP_014045.1	Ntn_hydrolase	6..217	CDD:469781	61/214 (29%)