Protein Alignment Prosalpha2 and PSMA7

DIOPT Version :10

• Sequence 1: NP_524328.1
• Gene: Prosalpha2 / 41531
• FlyBaseID: FBgn0086134
• Length: 234
• Species: Drosophila melanogaster
• Sequence 2: NP_002783.1
• Gene: PSMA7 / 5688
• HGNCID: 9536
• Length: 248
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 89/236 - (37%)
• Similarity: 143/236 - (60%)
• Gaps: 14/236 - (5%)

  Fly     6 YSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMIYN 70
            |..::|.|||.|.|.|:|||..||..|:.:||:...:.||:..|.|..:.|.::.:|.::..:.:
Human     3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALDD 67

  Fly    71 HIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVRPFGVSLL 135
            ::.|.::|:..|.|:::.:||...|::.||.::|:.|..:.:.:|:|.|.||||.|.||||:|.|
Human    68 NVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISAL 132

  Fly   136 ICGWDND-RPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELDDAVHTAILTLKEGF 199
            |.|:|.| .|.|||:||||.|.||||.|:|:.|.:.:.||||.|:     |:|:.|..||:|...
Human   133 IVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT-----DEAIETDDLTIKLVI 192

  Fly   200 EGKMT-----ADNIEIGIC--DQNGFQRLDPASIKDYLASI 233
            :..:.     ..|||:.:.  ||: .:.|:|..|:.|:|.|
Human   193 KALLEVVQSGGKNIELAVMRRDQS-LKILNPEEIEKYVAEI 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha2	NP_524328.1	proteasome_alpha_type_2	6..231	CDD:239719	87/232 (38%)
PSMA7	NP_002783.1	proteasome_alpha_type_7	3..211	CDD:239724	81/212 (38%)