DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha2 and Psma4

DIOPT Version :9

Sequence 1:	NP_524328.1	Gene:	Prosalpha2 / 41531	FlyBaseID:	FBgn0086134	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_036096.1	Gene:	Psma4 / 26441	MGIID:	1347060	Length:	261	Species:	Mus musculus

Alignment Length:	214	Identity:	85/214 - (39%)
Similarity:	124/214 - (57%)	Gaps:	8/214 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TERYSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEM 67
            :.||....|.|||.|:|.|:|||:.|:......:||:|::||::|.|.::...|.::  |...|.
Mouse     2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDE--VFFSEK 64

  Fly    68 IY---NHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVRP 129
            ||   ..:....:|:..|..:|..:.|.|||.|.|.|:||||..|||..:..:.|.|||.||.||
Mouse    65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRP 129

  Fly   130 FGVSLLICGWDNDRPY-LYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSE-DLELDDAVHTAI 192
            ||||||..|||....: ||||||||.|..||||.:|.|:....:.|::.|.| ::.|..|:..|:
Mouse   130 FGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAV 194

  Fly   193 LTLKEGFE-GKMTADNIEI 210
            ..|.:..: .|::|:.:||
Mouse   195 KVLNKTMDVSKLSAEKVEI 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha2	NP_524328.1	proteasome_alpha_type_2	6..231	CDD:239719	84/211 (40%)
Psma4	NP_036096.1	proteasome_alpha_type_4	3..216	CDD:239721	85/213 (40%)
Psma4	NP_036096.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..261
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920