DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha2 and PSMA8

DIOPT Version :9

Sequence 1:NP_524328.1 Gene:Prosalpha2 / 41531 FlyBaseID:FBgn0086134 Length:234 Species:Drosophila melanogaster
Sequence 2:NP_653263.2 Gene:PSMA8 / 143471 HGNCID:22985 Length:256 Species:Homo sapiens


Alignment Length:243 Identity:97/243 - (39%)
Similarity:144/243 - (59%) Gaps:20/243 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RYSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMIY 69
            ||..::|.|||.|.|.|:|||..||..|:.:|||..:|.||:..|.|..:.|.::.:|.::..:.
Human     4 RYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALD 68

  Fly    70 NHIGM------VYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVR 128
            :|:.|      ::.|:..|.|:::.:||...|::.||.::|:.|..:.:.:|||.|:||||.|.|
Human    69 DHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRR 133

  Fly   129 PFGVSLLICGWDNDR-PYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELDD--AVHT 190
            |||:|.||.|:|:|. ..|||:||||.|.||||.|:|::|...:.||||.|:||....|  |:..
Human   134 PFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKL 198

  Fly   191 AILTLKEGFE--GKMTADNIEIGICDQNGFQRLDPASIKD---YLASI 233
            ||..|.|..:  ||    |||:.|..:|  |.|...|.|:   |:..|
Human   199 AIKALLEVVQSGGK----NIELAIIRRN--QPLKMFSAKEVELYVTEI 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha2NP_524328.1 proteasome_alpha_type_2 6..231 CDD:239719 95/238 (40%)
PSMA8NP_653263.2 PRK03996 5..237 CDD:235192 94/237 (40%)
proteasome_alpha_type_7 5..219 CDD:239724 88/217 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1222564at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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