Protein Alignment CG5245 and ZSCAN10

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_116194.2
• Gene: ZSCAN10 / 84891
• HGNCID: 12997
• Length: 780
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 161/455 - (35%)
• Similarity: 220/455 - (48%)
• Gaps: 45/455 - (9%)

  Fly    68 KIAKKRPLRKQTDTFKCTQCQKTFTRKENLESH-LRLHAEERPFECSHCSKSFGRRTHYKRHLLK 131
            |:|:..|.......|.|..|..:|.:...|::| ||.|...|.|.|..|.|||||.:..|.|:..
Human   333 KVAEGVPEPNPELQFICADCGVSFPQLSRLKAHQLRSHPAGRSFLCLCCGKSFGRSSILKLHMRT 397

  Fly   132 H-EKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFEC 195
            | ::|||.|..|...|.|:|.|.:||..|:.|..|.|.:|...|.|::.|..||..|::::...|
Human   398 HTDERPHACHLCGHRFRQSSHLSKHLLTHSSEPAFLCAECGRGFQRRASLVQHLLAHAQDQKPPC 462

  Fly   196 THCEKAFKNNSHLQEHLRTHQEARPFK---CSHCSKSFKLRSILQKHLLTHA------------- 244
            ....||               ||.|..   ||||.:||:.||.|::||..||
Human   463 APESKA---------------EAPPLTDVLCSHCGQSFQRRSSLKRHLRIHARDKDRRSSEGSGS 512

  Fly   245 ------ERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEP 303
                  .|.|.|:.|.|.|.:::.|..|.|||.||.||.|..|..:|.::|:|..|...|.|::|
Human   513 RRRDSDRRPFVCSDCGKAFRRSEHLVAHRRVHTGERPFSCQACGRSFTQSSQLVSHQRVHTGEKP 577

  Fly   304 LKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKD 368
            ..|.||...|..|:....|:..|...|.:.|.:|.|||.:...|..||:.||||:|.:|:.|.:.
Human   578 YACPQCGKRFVRRASLARHLLTHGGPRPHHCTQCGKSFGQTQDLARHQRSHTGEKPCRCSECGEG 642

  Fly   369 FKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHM 433
            |....||..|...|.|||...|..|...|:.||.|..|.:.|||:..:.|..|.:|:..::.|..
Human   643 FSQSAHLARHQRIHTGEKPHACDTCGHRFRNSSNLARHRRSHTGERPYSCQTCGRSFRRNAHLRR 707

  Fly   434 HLRTHT------GELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            ||.||.      .|.|.:|..|.|.|:||.....||..|||.:||.|:.|...:::.|.|.||||
Human   708 HLATHAEPGQEQAEPPQECVECGKSFSRSCNLLRHLLVHTGARPYSCTQCGRSFSRNSHLLRHLR 772

  Fly   493  492
            Human   773  772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	152/433 (35%)
		C2H2 Zn finger	84..104	CDD:275368	7/20 (35%)
		C2H2 Zn finger	112..132	CDD:275368	9/19 (47%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	7/19 (37%)
		C2H2 Zn finger	195..215	CDD:275368	3/19 (16%)
		C2H2 Zn finger	223..243	CDD:275368	11/19 (58%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)
ZSCAN10	NP_116194.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		SCAN	40..124	CDD:153421
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..237
		PHA03418	156..>314	CDD:177646
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..324
		C2H2 Zn finger	349..370	CDD:275368	7/20 (35%)
		C2H2 Zn finger	378..398	CDD:275368	9/19 (47%)
		COG5048	400..774	CDD:227381	137/388 (35%)
		C2H2 Zn finger	406..426	CDD:275368	8/19 (42%)
		C2H2 Zn finger	434..454	CDD:275368	7/19 (37%)
		C2H2 Zn finger	478..498	CDD:275368	11/19 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	492..520		4/27 (15%)
		C2H2 Zn finger	524..544	CDD:275368	7/19 (37%)
		C2H2 Zn finger	552..572	CDD:275368	6/19 (32%)
		C2H2 Zn finger	580..600	CDD:275368	6/19 (32%)
		C2H2 Zn finger	608..628	CDD:275368	8/19 (42%)
		C2H2 Zn finger	636..656	CDD:275368	6/19 (32%)
		C2H2 Zn finger	664..684	CDD:275368	7/19 (37%)
		C2H2 Zn finger	692..712	CDD:275368	6/19 (32%)
		C2H2 Zn finger	728..746	CDD:275368	7/17 (41%)
		C2H2 Zn finger	754..774	CDD:275368	8/19 (42%)