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Protein Alignment CG5245 and ZNF221

DIOPT Version :10

Sequence 1:	NP_650197.1	Gene:	CG5245 / 41530	FlyBaseID:	FBgn0038047	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_037491.2	Gene:	ZNF221 / 7638	HGNCID:	13014	Length:	617	Species:	Homo sapiens

Alignment Length:	556	Identity:	180/556 - (32%)
Similarity:	261/556 - (46%)	Gaps:	74/556 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VKDEPPQEDTFEEELIFISNSDFEELESEIKIENFCSYGK---DLEPV---------------KG 57
            |.::|..:|||.    |:....|.::::..:.|. .|.||   ::|.|               :.
Human    69 VGNQPFHQDTFH----FLGKEKFWKMKTTSQREG-NSGGKIQIEMETVPEAGPHEEWSCQQIWEQ 128

  Fly    58 VPSKLKTCKSKIAKKRPLRKQTDT-----------------FKCTQCQKTFTRKENLESHLRLHA 105
            :.|.|...::.|.......|:.|.                 ::|.:|:::|:.....:.|.:.|:
Human   129 IASDLTRSQNSIRNSSQFFKEGDVPCQIEARLSISHVQQKPYRCNECKQSFSDVSVFDLHQQSHS 193

  Fly   106 EERPFECSHCSKSF----GRRTHYKRHLLKHEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFK 166
            .|:...|..|.|||    ....|.:.|:   .::.:||..|.|.|.|:|.|:.|...||||:|||
Human   194 GEKSHTCGECGKSFCYSPALHIHQRVHM---GEKCYKCDVCGKEFNQSSHLQTHQRVHTGEKPFK 255

  Fly   167 CTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFK 231
            |.||...|..:|.|.||.:.|:.|:|:.|..|.|||.::|.||||.|.|...:||||..|.|||:
Human   256 CGQCGKGFHSRSALNVHCKLHTGEKPYNCEECGKAFIHDSQLQEHQRIHTGEKPFKCDICGKSFR 320

  Fly   232 LRSILQKHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHL 295
            :||.|.:|.:.| .|:.|:|..|.|.|.|..:|..|..||..|.|:||..|.:.|........|.
Human   321 VRSRLNRHSMVHTGEKPFRCDTCGKNFRQRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFCKHQ 385

  Fly   296 LEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPF 360
            :.|.|::|..|.:|..||...|....|.::|:.::.:||.||.|.|:..|....||:.|.||:|:
Human   386 MVHTGEKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYTNSRRSSHQRSHNGEKPY 450

  Fly   361 KCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSY 425
            .|..|.||:|.|..|..|...|.||:...|..|.|.|..:|.||.|.:.|:|:..|:|..|.|.:
Human   451 NCEECGKDYKRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLKHQRLHSGEKPFKCEECGKRF 515

  Fly   426 TTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRH 490
            |.||.||.|...||||..:||..|.|.:........|.|.|.||:||.|..|...:...|.|.:|
Human   516 TQSSQLHSHQTCHTGEKLYKCEQCEKGYNSKFNLDMHQRVHGGERPYNCKECGKSFGWASCLLKH 580

  Fly   491 LRR--------------------------TLCGTKS 500
            .|.                          :|||.|:
Human   581 QRLHSGEKPLKSGVWEEIYSEFTASFTSVSLCGRKA 616

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.