Protein Alignment CG5245 and Zfp946

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001318124.1
• Gene: Zfp946 / 74149
• MGIID: 1921399
• Length: 545
• Species: Mus musculus
• Alignment Length: 532
• Identity: 169/532 - (31%)
• Similarity: 246/532 - (46%)
• Gaps: 92/532 - (17%)

  Fly    21 FEEELIFISNSDFEELE-------SEIKIEN-----FCSYGKDLEPVKGVPSKLKTCKSKIAKK- 72
            |::..:..|..::|.|:       .::.:||     |..:.::    ..:..|.|....:.|::
Mouse    37 FKDVAVEFSQEEWECLDCAQRALYMDVMLENYNNLFFVVFSEN----DHICYKYKNVLDEDAQQI 97

  Fly    73 --RPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFE------------------------ 111
              :.|..|..::||.:..| .|......|..:::..:...|
Mouse    98 VHQHLNIQEKSYKCHELAK-ITHASTQNSPYKINLRDTTVESSKLNRHRTGNIREPCKYKNCVNC 161

  Fly   112 ---CSHCSKSFGRRTHYKRH---------------LLK---HEKRPHKCSHCSKTFTQNSSLKQH 155
               ||..|.:.|...:.|.|               :||   ..|:|:|||.|.:.|||...||.|
Mouse   162 LSVCSIISLNQGIHINKKEHNGTEFDKIFESKEKRMLKPTNSGKKPYKCSECEECFTQLCDLKSH 226

  Fly   156 LHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARP 220
            ...|.||:..|.::....||.||.|::|...|:..:|::|..|.|:|...|.|:.|.|.|...:|
Mouse   227 QRNHIGEKLCKSSEHDNCFALKSDLRIHQPVHTRGKPYKCNECIKSFTQKSSLKRHQRIHTGEKP 291

  Fly   221 FKCSHCSKSFKLRSILQKHLLTHAERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETF 285
            :|||.|:|.|.     .|::|.                      ||.::|.||.|:||..|.:.|
Mouse   292 YKCSECNKCFS-----HKYILI----------------------IHQKIHTGEKPYKCNACGKCF 329

  Fly   286 ARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEH 350
            .....|::|...|.|::|.|||:|..:|..:....:|.|:||.|:.|||:||.|.|.||..||.|
Mouse   330 TLKGELRIHQRIHTGEKPYKCSECDKSFTQKGQLIIHQRIHTGEKPYKCSECDKCFIKKYSLVTH 394

  Fly   351 QQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQ 415
            |::||||.|:||:.|.|.|..::.||:|...|.|||..|||.|.|.|.....|.:|...|.|:..
Mouse   395 QRMHTGENPYKCSECDKCFTLKSGLRIHERIHTGEKPYKCSECDKSFIKKIYLRIHQSVHIGEKL 459

  Fly   416 FECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTR 480
            ::|..|.|.:....:|..|.|.||||.|:|||.|.|.|........|.|.|||||||:||.|...
Mouse   460 YKCSECDKCFMHKCSLSSHQRLHTGEKPYKCSICDKCFTSKGYLGSHQRIHTGEKPYQCSECDKC 524

  Fly   481 YTQKSSLGRHLR 492
            :|.|.||.||.|
Mouse   525 FTHKGSLKRHER 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	151/448 (34%)
		C2H2 Zn finger	84..104	CDD:275368	4/19 (21%)
		C2H2 Zn finger	112..132	CDD:275368	8/37 (22%)
		C2H2 Zn finger	139..159	CDD:275368	9/19 (47%)
		C2H2 Zn finger	167..187	CDD:275368	6/19 (32%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	2/19 (11%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	11/19 (58%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	9/17 (53%)
Zfp946	NP_001318124.1	C2H2 Zn finger	490..510	CDD:275368	7/19 (37%)
		C2H2 Zn finger	518..538	CDD:275368	10/19 (53%)
		KRAB	37..74	CDD:460171	6/36 (17%)
		C2H2 Zn finger	210..230	CDD:275368	9/19 (47%)
		COG5048	262..>545	CDD:227381	120/302 (40%)
		C2H2 Zn finger	266..286	CDD:275368	8/19 (42%)
		C2H2 Zn finger	294..314	CDD:275368	9/46 (20%)
		C2H2 Zn finger	322..342	CDD:275368	5/19 (26%)
		C2H2 Zn finger	350..370	CDD:275368	6/19 (32%)
		C2H2 Zn finger	378..398	CDD:275368	11/19 (58%)
		C2H2 Zn finger	406..426	CDD:275368	7/19 (37%)
		C2H2 Zn finger	434..454	CDD:275368	7/19 (37%)
		C2H2 Zn finger	462..482	CDD:275368	6/19 (32%)