Protein Alignment CG5245 and Zfp426

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001073412.1
• Gene: Zfp426 / 690895
• RGDID: 1590942
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 157/504 - (31%)
• Similarity: 244/504 - (48%)
• Gaps: 40/504 - (7%)

  Fly     2 DLANVDQRPVKDEPPQEDTFEEELIFISNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCK 66
            :||.|..:.:|   |...::.|:..|.:.......|.:|::|..||           .|:.:..:
  Rat    75 NLATVGYQLIK---PSVISWLEQEEFSTGQKIVFPEWKIQLETQCS-----------ASQQELLR 125

  Fly    67 SKIAKKRPLRKQTDTFK--C--TQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKR 127
            ..|:.....:..:||.:  |  ||....|:....|.:.::....:..::.|.|.|.|
  Rat   126 GNISNGMQTQTGSDTGRGLCDGTQYGDFFSELSPLRTVMKTRPAQDNYDSSQCRKDF-------- 182

  Fly   128 HLLKHEKRPHKCS-HCSKTFTQNSSL-----KQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRT 186
             |:...|   ||: .....|.|:...     |.:....|.|:.|:|:.|..||..:||||.|.||
  Rat   183 -LMLQRK---KCAGEKLSEFNQSEETGAIPGKAYQKMATQEKCFECSDCGKSFMNQSHLQTHQRT 243

  Fly   187 HSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKC 250
            ||.::.:|...|.::| .||.|...:.|....:|.:|..|.|.::..:.|..|:.|| .|:.::|
  Rat   244 HSGDKLYELNECGRSF-INSRLAVLIETLNAKKPHRCKECGKGYRYPAYLNIHMRTHTGEKPYEC 307

  Fly   251 TQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAM 315
            .:|.|.|..::|.|||.|.|.||.|:.|..|.:.|.::|.|.:|:..|.|.:|..|.:|...|..
  Rat   308 KECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQHSGLSIHVRSHNGDKPYACKECGKAFLT 372

  Fly   316 RSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHML 380
            .|....|:|.||.|:.:.|.:|.|:|...|:|..|.::|..|:..:|..|.|.|...:.|..||.
  Rat   373 SSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYLSCLNNHMR 437

  Fly   381 DHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFK 445
            .|..:|...|..|.|.|..|:.|.:|::.|||:..:||..|.|:::.|::..:|.||||||.|::
  Rat   438 THNAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSFQIHERTHTGEKPYE 502

  Fly   446 CSHCSKLFARSAEHQEH--LRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            |..|.|.|...:..:.|  ..|||.||||||..|...|:...||.||.|
  Rat   503 CKECGKAFICPSSFRIHEISHTHTEEKPYKCQQCGKAYSHPRSLRRHER 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	136/416 (33%)
		C2H2 Zn finger	84..104	CDD:275368	5/21 (24%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	4/25 (16%)
		C2H2 Zn finger	167..187	CDD:275368	10/19 (53%)
		C2H2 Zn finger	195..215	CDD:275368	5/19 (26%)
		C2H2 Zn finger	223..243	CDD:275368	5/19 (26%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	7/19 (37%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	5/21 (24%)
		C2H2 Zn finger	474..492	CDD:275368	7/17 (41%)
Zfp426	NP_001073412.1	KRAB	40..97	CDD:214630	6/24 (25%)
		zf-C2H2	222..244	CDD:395048	11/21 (52%)
		C2H2 Zn finger	224..244	CDD:275368	10/19 (53%)
		C2H2 Zn finger	279..299	CDD:275368	5/19 (26%)
		zf-H2C2_2	291..316	CDD:463886	9/24 (38%)
		C2H2 Zn finger	307..327	CDD:275368	9/19 (47%)
		COG5048	<331..483	CDD:227381	51/151 (34%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)
		C2H2 Zn finger	363..383	CDD:275368	6/19 (32%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		C2H2 Zn finger	419..439	CDD:275368	7/19 (37%)
		C2H2 Zn finger	447..467	CDD:275368	7/19 (37%)
		C2H2 Zn finger	475..495	CDD:275368	6/19 (32%)
		zf-H2C2_2	487..512	CDD:463886	12/24 (50%)
		C2H2 Zn finger	503..523	CDD:275368	5/19 (26%)
		C2H2 Zn finger	533..553	CDD:275368	8/19 (42%)