Protein Alignment CG5245 and Gm7072

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001344920.1
• Gene: Gm7072 / 631624
• MGIID: 3648314
• Length: 689
• Species: Mus musculus
• Alignment Length: 479
• Identity: 188/479 - (39%)
• Similarity: 261/479 - (54%)
• Gaps: 38/479 - (7%)

  Fly    52 LEPVKGV--PSKLKTCK------SKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEER 108
            |:..|.|  |.|...|:      ..:.|.:.:.|....:||.:|:|.|:.|.:|.:|.|:|..|.
Mouse   173 LKQTKSVKKPYKCSECEKCFIQVGDLRKHQRIHKGEKPYKCNECEKCFSYKSSLRTHQRIHTGEN 237

  Fly   109 PFECSHCSKSFGRRTHYKRHLLKHE-KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCST 172
            |::||.|.|.|..:.....|.:.|. |:|:|||.|.|.|.|...|::|...||||:|:||.:|..
Mouse   238 PYKCSECDKCFSHKGSLSIHQMYHTGKKPYKCSECEKCFIQVGDLRRHERIHTGEKPYKCNECEK 302

  Fly   173 SFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQ 237
            .|:.|::|:.|.|.|:.|:|::|:.|:|.|.....|..|...|...:|:|||.|.|.|.....|:
Mouse   303 CFSSKTNLRTHQRIHTGEKPYKCSECDKGFTLKCSLIIHQVYHTGKKPYKCSECEKCFIQVGDLR 367

  Fly   238 KHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGK 301
            ||...| .|:.:||::|.|:|.|..||.||.|:||||.|::|..|.:.|.....|.:|.:.|.|:
Mouse   368 KHQRIHTGEKPYKCSECDKSFTQKGSLSIHQRIHAGEKPYRCSECDKGFTLKCSLIIHQIIHTGE 432

  Fly   302 EPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCF 366
            :..|||:|...|:.:...:||:|:||.|..|||:||.|.|.||..|..||.:||||:|:||:.|.
Mouse   433 KTYKCSECDKCFSHKGSLKVHLRIHTGENLYKCSECDKCFTKKWRLTSHQTIHTGEKPYKCSECD 497

  Fly   367 KDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTL 431
            |.|..:.:||.|...|.|||..|||.|.|.:...|.|:||.:.|.|:..::|..|.|.||..|.|
Mouse   498 KSFTLKGNLRDHQRIHTGEKPYKCSECDKYYTRKSHLIVHQKIHAGEKPYKCSECDKYYTRKSHL 562

  Fly   432 HMHLRTHTGELPFKCSHCSKLFARS---AEHQE-------------------------HLRTHTG 468
            .:|.|.|.||.|:|||.|:|.|...   ..||.                         |.|.|||
Mouse   563 IVHQRIHIGEKPYKCSECNKCFTNKYHLRTHQRIHSANKPYKCSECDKCFTEKYRLIIHQRIHTG 627

  Fly   469 EKPYKCSHCSTRYTQKSSLGRHLR 492
            |||||||.|...:|:||||..|.|
Mouse   628 EKPYKCSECDKYFTRKSSLNVHQR 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	173/433 (40%)
		C2H2 Zn finger	84..104	CDD:275368	8/19 (42%)
		C2H2 Zn finger	112..132	CDD:275368	6/19 (32%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	7/19 (37%)
		C2H2 Zn finger	195..215	CDD:275368	6/19 (32%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	10/19 (53%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	10/19 (53%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	9/19 (47%)
		C2H2 Zn finger	446..466	CDD:275368	9/47 (19%)
		C2H2 Zn finger	474..492	CDD:275368	9/17 (53%)
Gm7072	NP_001344920.1	KRAB	13..52	CDD:460171
		C2H2 Zn finger	185..205	CDD:275368	2/19 (11%)
		COG5048	209..650	CDD:227381	178/440 (40%)
		C2H2 Zn finger	213..233	CDD:275368	8/19 (42%)
		C2H2 Zn finger	241..261	CDD:275368	6/19 (32%)
		C2H2 Zn finger	269..289	CDD:275368	8/19 (42%)
		C2H2 Zn finger	297..317	CDD:275368	7/19 (37%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	353..373	CDD:275368	8/19 (42%)
		C2H2 Zn finger	381..401	CDD:275368	10/19 (53%)
		C2H2 Zn finger	409..429	CDD:275368	5/19 (26%)
		C2H2 Zn finger	437..457	CDD:275368	7/19 (37%)
		C2H2 Zn finger	465..485	CDD:275368	10/19 (53%)
		C2H2 Zn finger	493..513	CDD:275368	7/19 (37%)
		C2H2 Zn finger	521..541	CDD:275368	8/19 (42%)
		C2H2 Zn finger	549..569	CDD:275368	9/19 (47%)
		C2H2 Zn finger	577..597	CDD:275368	7/19 (37%)
		C2H2 Zn finger	605..625	CDD:275368	2/19 (11%)
		C2H2 Zn finger	633..653	CDD:275368	10/19 (53%)
		zf-H2C2_2	645..669	CDD:463886	4/7 (57%)
		C2H2 Zn finger	661..681	CDD:275368