Protein Alignment CG5245 and Zfp970

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001171039.1
• Gene: Zfp970 / 628308
• MGIID: 3652255
• Length: 522
• Species: Mus musculus
• Alignment Length: 505
• Identity: 193/505 - (38%)
• Similarity: 280/505 - (55%)
• Gaps: 18/505 - (3%)

  Fly     1 MDLANVDQRPVKDEPPQEDTFEEELIFISNSDFEELESEIKIE---NFCSYGKDLEPVKGVPSKL 62
            |||...|...|        .|.:|...:.::..:.|...:.:|   |..:.|...|. ..:....
Mouse     1 MDLVTYDDVHV--------NFTQEEWALLDASQKSLYKGVMVETYRNLTAIGYSWEE-HTIEDHF 56

  Fly    63 KTCKSK-IAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYK 126
            :|.:|. ..::|...:|...|  .||.|.|..:.:.:.|:|:|..|:.:||:.|.|.||.|:..:
Mouse    57 QTSRSHGRYERRSSAEQHSEF--IQCGKAFACQSHSQRHVRIHNGEKHYECNQCGKDFGTRSVLQ 119

  Fly   127 RHLLKHE-KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEE 190
            |....|. ::|::|:||.|.|.::|:|:.|..:|||:.|::|..|..:||::|.||:|.|.|:.|
Mouse   120 RLKRTHTGEKPYECNHCGKAFAESSTLQIHKRKHTGDEPYECNHCVKAFAKRSDLQIHKRIHTGE 184

  Fly   191 RPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCP 254
            :|:||..|.|||..:|||..|.|||...:|::|..|.|:|...|.||.|..|| .|:.::|.||.
Mouse   185 KPYECNQCGKAFTRSSHLGIHKRTHTGEKPYECKQCGKAFARSSTLQTHKHTHTGEKPYECKQCG 249

  Fly   255 KTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLY 319
            |.|.|:..||||.|.|..|.|::|..|.:.||.:|.||:|...|.|::|.:|.||...|..|...
Mouse   250 KAFAQSGPLQIHKRTHTAEKPYECKQCGKAFAHSSTLQIHKRTHTGEKPYECKQCDKAFVKRGEL 314

  Fly   320 RVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIG 384
            ::|.|.||.|:.|:|.:|.|:|.:...|.||::.||||:||:|..|.|.|.....||:|...|.|
Mouse   315 QIHKRTHTGEKPYECKQCGKAFAQSGTLQEHERTHTGEKPFECNQCGKAFVRCIALRIHERTHTG 379

  Fly   385 EKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHC 449
            ||..:|..|.|.|..|..|..|.:.|||:..|||..|.|::.....|.:|.||||||.|::|..|
Mouse   380 EKPYECKQCGKAFAQSGTLQGHERTHTGEKPFECNQCGKAFVQCIALRIHERTHTGEKPYECKQC 444

  Fly   450 SKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLRRTLCGTK 499
            .|.||..:..|.|.|||||||||:|..|...:..:|:|..| :||..|.|
Mouse   445 GKAFAHRSTLQIHERTHTGEKPYECKQCGKAFAHRSTLQIH-KRTHTGEK 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	170/405 (42%)
		C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		C2H2 Zn finger	112..132	CDD:275368	7/19 (37%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	10/19 (53%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	11/19 (58%)
		C2H2 Zn finger	278..298	CDD:275368	8/19 (42%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	7/19 (37%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Zfp970	NP_001171039.1	C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	413..433	CDD:275368	6/19 (32%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		C2H2 Zn finger	469..489	CDD:275368	6/20 (30%)
		zf-H2C2_2	482..506	CDD:463886	6/13 (46%)
		C2H2 Zn finger	497..517	CDD:275368
		KRAB	3..44	CDD:460171	8/48 (17%)
		COG5048	75..477	CDD:227381	170/403 (42%)
		C2H2 Zn finger	79..97	CDD:275368	6/17 (35%)
		C2H2 Zn finger	105..125	CDD:275368	7/19 (37%)
		C2H2 Zn finger	133..153	CDD:275368	8/19 (42%)
		C2H2 Zn finger	161..181	CDD:275368	9/19 (47%)
		C2H2 Zn finger	189..209	CDD:275368	10/19 (53%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	245..265	CDD:275368	11/19 (58%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)