Protein Alignment CG5245 and Zfp551

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001028992.2
• Gene: Zfp551 / 619331
• MGIID: 3588205
• Length: 696
• Species: Mus musculus
• Alignment Length: 516
• Identity: 187/516 - (36%)
• Similarity: 261/516 - (50%)
• Gaps: 65/516 - (12%)

  Fly    27 FISNSDFEELESEI---KIENFCSYGKDLEPVKGVPSKLKTCKSKIAKKRPLRKQT-DTFKCTQ- 86
            ||...|.||..|.|   :.:..|   ...:|..|...:..||         :|:|. .:.||.|
Mouse   193 FIRGKDGEEALSSIAGVQQQGAC---HSEQPSTGCLQQQATC---------IREQPYSSAKCGQA 245

  Fly    87 ------------CQKTFTRKENLESHLRLHAEERPFECSHCSKSF--------------GRRTHY 125
                        |||..:.|..|.......:|:||.|||...|:|              |:|||
Mouse   246 LLNGEKHCKDGECQKGSSCKHTLVQCPSASSEKRPSECSKYEKAFSCSYKHAQHQDSHSGKRTH- 309

  Fly   126 KRHLLKHEK------------------RPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCST 172
             .| .:|||                  ||:||:.|.|.|...|.|..|...|:....::|.:|..
Mouse   310 -EH-SQHEKPFSKKCRLNTQDRICPQERPYKCTECGKAFIYKSELVYHQRHHSARVHYECVECRK 372

  Fly   173 SFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQ 237
            ||..||:|..|.|.|:.|||::|..|.|:|:.||.|..|.|.|...||::||.|.|||:....|.
Mouse   373 SFTYKSNLTEHQRIHTGERPYQCEQCGKSFRQNSSLFRHHRIHTGERPYECSECGKSFRQIFNLI 437

  Fly   238 KHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGK 301
            :|...| .|...:|..|.|.|.....|..|.|:|:||.|::|..|.:.|.:.|.|..|...|.|.
Mouse   438 RHRRVHTGEMPHQCADCGKAFSCKAELSQHERIHSGEKPYECSECGKYFRQFSNLIRHRRVHTGD 502

  Fly   302 EPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCF 366
            .|.|||:|..:|:.:.:...|.|:||.||.|||.||..||.:||.|::||::|||.||::|..|.
Mouse   503 RPYKCSECEKSFSRKFILVQHQRVHTGERPYKCGECGTSFTRKSDLIQHQRIHTGTRPYECEECG 567

  Fly   367 KDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTL 431
            |.|:..:.|..|...|.|||..:|..|.|.|..|:.|:.|.:.|||:..:||..|.||::.|::|
Mouse   568 KSFRQCSSLIQHRRVHTGEKPYECIECGKAFSQSASLIQHQRLHTGERPYECSECGKSFSQSASL 632

  Fly   432 HMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            ..|.|:|:||.||:||.|||.|...::..:|.|.||||:||:|..|...::::|:|.||.|
Mouse   633 IQHQRSHSGEKPFECSDCSKPFTHKSDLIQHRRVHTGERPYECHDCEKSFSRRSNLVRHQR 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	169/450 (38%)
		C2H2 Zn finger	84..104	CDD:275368	7/32 (22%)
		C2H2 Zn finger	112..132	CDD:275368	9/33 (27%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	9/19 (47%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	10/19 (53%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)
Zfp551	NP_001028992.2	KRAB	48..88	CDD:460171
		C2H2 Zn finger	257..275	CDD:275368	5/17 (29%)
		C2H2 Zn finger	283..303	CDD:275368	4/19 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..319		8/21 (38%)
		C2H2 Zn finger	339..359	CDD:275368	7/19 (37%)
		COG5048	365..695	CDD:227381	138/329 (42%)
		C2H2 Zn finger	367..387	CDD:275368	9/19 (47%)
		C2H2 Zn finger	395..415	CDD:275368	9/19 (47%)
		C2H2 Zn finger	423..443	CDD:275368	8/19 (42%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		C2H2 Zn finger	479..499	CDD:275368	6/19 (32%)
		C2H2 Zn finger	507..527	CDD:275368	6/19 (32%)
		C2H2 Zn finger	535..555	CDD:275368	10/19 (53%)
		C2H2 Zn finger	563..583	CDD:275368	6/19 (32%)
		C2H2 Zn finger	591..611	CDD:275368	7/19 (37%)
		C2H2 Zn finger	619..639	CDD:275368	8/19 (42%)
		C2H2 Zn finger	647..667	CDD:275368	8/19 (42%)
		C2H2 Zn finger	675..695	CDD:275368	7/19 (37%)