Protein Alignment CG5245 and Zfp235

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001347394.1
• Gene: Zfp235 / 56525
• MGIID: 1929117
• Length: 772
• Species: Mus musculus
• Alignment Length: 491
• Identity: 188/491 - (38%)
• Similarity: 256/491 - (52%)
• Gaps: 31/491 - (6%)

  Fly     5 NVDQRPVKDEPPQEDTFEEELIFISNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCKSKI 69
            |..|....|.|.|    |.:.:.:.|.                     .||.|.........|.|
Mouse   303 NTGQDAFIDSPSQ----ETQQVLLGNK---------------------SPVHGTYEDTSYTSSVI 342

  Fly    70 AKK-RPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHE 133
            .:. .|.||:   :.|.:|.|.|::..||::|.|:|..|:|:.|..|.|||.:.:|...||..|.
Mouse   343 QQSVHPGRKR---YWCQECGKAFSQSSNLQTHQRVHTGEKPYTCPECGKSFNQSSHLYAHLPIHT 404

  Fly   134 -KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTH 197
             ::|:.|.:|.|.|::::.|..|...||||:|:||..|...|.::||||.|.|.|:.|:|::|..
Mouse   405 GEKPYCCDNCGKGFSRSTDLNIHCRVHTGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPYKCGD 469

  Fly   198 CEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCPKTFLQND 261
            |.|.|..:|:|..|.|.|.|.:|:||..|.|.|.|...|..|...| .|:.:||.:|.|.|....
Mouse   470 CGKCFSCSSNLHTHQRVHTEEKPYKCDECGKRFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSAS 534

  Fly   262 SLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLH 326
            |.|.|.|||.||.||.|..|.:.|:::|..|.|...|.|::|.:|..|...|........|.|:|
Mouse   535 SFQSHQRVHTGEKPFCCSVCGKGFSQSSYFQAHQRVHTGEKPYRCDVCGKRFNWSLNLHNHQRVH 599

  Fly   327 TRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCS 391
            |.||.|||.||.|.|.:.|:|..||.|||||:||:|..|.|.|...:||:.|...|.||:..||.
Mouse   600 TGERPYKCEECGKGFSQASNLQAHQSVHTGEKPFRCNACQKRFSQASHLQAHQRVHTGERPYKCD 664

  Fly   392 YCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARS 456
            .|.|.|...|.|.||...|||:..|:|..|.|.::.|:.|..|.|.||||.|:.|..|.|.|:::
Mouse   665 TCGKAFSQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLTAHQRVHTGEKPYTCQQCGKGFSQA 729

  Fly   457 AEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            :....|.|.||||:||.||.||..::|:|.|..|.|
Mouse   730 SHFHTHQRVHTGERPYICSICSKGFSQRSHLVYHQR 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	169/405 (42%)
		C2H2 Zn finger	84..104	CDD:275368	8/19 (42%)
		C2H2 Zn finger	112..132	CDD:275368	8/19 (42%)
		C2H2 Zn finger	139..159	CDD:275368	6/19 (32%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
		C2H2 Zn finger	334..354	CDD:275368	9/19 (47%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..492	CDD:275368	8/17 (47%)
Zfp235	NP_001347394.1	KRAB	8..48	CDD:460171
		COG5048	355..696	CDD:227381	142/340 (42%)
		C2H2 Zn finger	355..375	CDD:275368	8/19 (42%)
		C2H2 Zn finger	383..403	CDD:275368	8/19 (42%)
		C2H2 Zn finger	411..431	CDD:275368	6/19 (32%)
		C2H2 Zn finger	439..459	CDD:275368	9/19 (47%)
		C2H2 Zn finger	467..487	CDD:275368	8/19 (42%)
		C2H2 Zn finger	495..515	CDD:275368	7/19 (37%)
		C2H2 Zn finger	523..543	CDD:275368	8/19 (42%)
		C2H2 Zn finger	551..571	CDD:275368	6/19 (32%)
		C2H2 Zn finger	579..599	CDD:275368	5/19 (26%)
		C2H2 Zn finger	607..627	CDD:275368	9/19 (47%)
		C2H2 Zn finger	635..655	CDD:275368	7/19 (37%)
		C2H2 Zn finger	663..683	CDD:275368	8/19 (42%)
		SFP1	<685..768	CDD:227516	35/81 (43%)
		C2H2 Zn finger	691..711	CDD:275368	7/19 (37%)
		C2H2 Zn finger	719..739	CDD:275368	6/19 (32%)
		C2H2 Zn finger	747..767	CDD:275368	9/19 (47%)