Protein Alignment CG5245 and ZNF117

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_056936.2
• Gene: ZNF117 / 51351
• HGNCID: 12897
• Length: 483
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 159/428 - (37%)
• Similarity: 227/428 - (53%)
• Gaps: 14/428 - (3%)

  Fly    57 GVPSKLKTCKSKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGR 121
            |:...|||..|||            |:|.:..:.|.:..|...|...|.|.:.|:|..|.|:|..
Human    68 GLNQCLKTTLSKI------------FQCNKYVEVFHKISNSNRHKMRHTENKHFKCKECRKTFCM 120

  Fly   122 RTHYKRH-LLKHEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLR 185
            .:|..:| .::.....:||....:.|..:|:|.:|...||||:|:||.:|..:|.:.|||..|.|
Human   121 LSHLTQHKRIQTRVNFYKCEAYGRAFNWSSTLNKHKRIHTGEKPYKCKECGKAFNQTSHLIRHKR 185

  Fly   186 THSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFK 249
            .|:||:|::|..|.|||..:|.|..|...|....|:||..|.::|...|.|.:|.|.| .|:.::
Human   186 IHTEEKPYKCEECGKAFNQSSTLTTHNIIHTGEIPYKCEKCVRAFNQASKLTEHKLIHTGEKRYE 250

  Fly   250 CTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFA 314
            |.:|.|.|.::..|..|..:|.||..:||..|.:.|.::|.|..|...|:|::|.||.:|...|.
Human   251 CEECGKAFNRSSKLTEHKYIHTGEKLYKCEECGKAFNQSSTLTTHKRIHSGEKPYKCEECGKAFK 315

  Fly   315 MRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHM 379
            ..|....|.::||.|:.|||.||.|:|.:.|:|..|:.:||||:|:||..|.|.|...:.|..|.
Human   316 QFSNLTDHKKIHTGEKPYKCEECGKAFNQLSNLTRHKVIHTGEKPYKCGECGKAFNQSSALNTHK 380

  Fly   380 LDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPF 444
            :.|.||...||....|.|.|||:|....:.|||:..::|..|.|::..||||..|.|.||||.|:
Human   381 IIHTGENPHKCRESGKVFHLSSKLSTCKKIHTGEKLYKCEECGKAFNRSSTLIGHKRIHTGEKPY 445

  Fly   445 KCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYT 482
            ||..|.|.|.:|:....|...||.||.|||..|....|
Human   446 KCEECGKAFNQSSTLTTHKIIHTEEKQYKCDECGKAST 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	150/405 (37%)
		C2H2 Zn finger	84..104	CDD:275368	4/19 (21%)
		C2H2 Zn finger	112..132	CDD:275368	6/20 (30%)
		C2H2 Zn finger	139..159	CDD:275368	5/19 (26%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	9/19 (47%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..492	CDD:275368	3/9 (33%)
ZNF117	NP_056936.2	C2H2 Zn finger	111..131	CDD:275368	6/19 (32%)
		C2H2 Zn finger	139..159	CDD:275368	5/19 (26%)
		COG5048	163..>475	CDD:227381	124/311 (40%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..299	CDD:275368	6/19 (32%)
		C2H2 Zn finger	307..327	CDD:275368	5/19 (26%)
		C2H2 Zn finger	335..355	CDD:275368	8/19 (42%)
		C2H2 Zn finger	363..383	CDD:275368	6/19 (32%)
		C2H2 Zn finger	391..407	CDD:275368	7/15 (47%)
		C2H2 Zn finger	419..439	CDD:275368	9/19 (47%)
		C2H2 Zn finger	447..467	CDD:275368	6/19 (32%)