Protein Alignment CG5245 and Zfp583

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001128081.2
• Gene: Zfp583 / 499068
• RGDID: 1562044
• Length: 568
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 168/514 - (32%)
• Similarity: 251/514 - (48%)
• Gaps: 72/514 - (14%)

  Fly     6 VDQRPVKDEPPQEDTFEEELIFISNSDFEELESEIKI---ENF-----CSYGKDLEPVKG-VPSK 61
            |.::..:|..|..:...:...|||..|..:..:::..   .:|     ||..|:....|. ..::
  Rat    67 VQKKGARDTCPDWEYVFKSTEFISKQDIYKASAKVLTMGRSHFSSRFDCSNLKENHESKDWFKNR 131

  Fly    62 L---KTCKSK--IAKKRPLRKQTDTFKCT-QCQ-----------KTFTRKENL---ESHLRLHAE 106
            |   :.|.|:  |..|.....|:..  |. .||           ::|:.||.:   |...|.: .
  Rat   132 LGGQEVCSSQSLITHKEVPENQSSV--CNPSCQAFHQDAILDTPQSFSTKERIDQSEPQKRSY-R 193

  Fly   107 ERPFECSHCSKSFGRRTHYKRHLLKHEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCS 171
            ::|.|..|      ::.|.::.:|       ||:.|.|.|.|:|||..|...||||:|:.|.:|.
  Rat   194 KKPIEMKH------KKVHVEKKIL-------KCTECEKVFNQSSSLTLHQRIHTGEKPYACVECG 245

  Fly   172 TSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSIL 236
            .:|::.::|..|.|.|:.|:|:||..|.|||..|:||.:|.|.|...:|::|..|.|:|.
  Rat   246 KAFSQSANLAQHKRIHTGEKPYECKECRKAFSQNAHLAQHQRVHTGEKPYQCKECKKAFS----- 305

  Fly   237 QKHLLTHAERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGK 301
                                  |...|..|.|:|.||.||:|..|.:.|:..|.|..|...|.|:
  Rat   306 ----------------------QIAHLTQHQRIHTGERPFECIECGKAFSNGSFLAQHQRIHTGE 348

  Fly   302 EPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCF 366
            :|..|..|...|:.|....||.|:||.||.|:|.||.|||.:.:||.:||:|||||:|::|..|.
  Rat   349 KPYVCHVCGKAFSHRGYLIVHQRIHTGERPYECKECRKSFSQYAHLSQHQRVHTGEKPYECKVCR 413

  Fly   367 KDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTL 431
            |.|....:|..|...|.|||..:|:.|.|.|..||.|..|.:.|||:..:.|..|.|:::.::.|
  Rat   414 KAFSQIAYLDQHQRVHTGEKPYECAECRKAFSNSSSLAQHQRSHTGEKPYICKECRKTFSQNAGL 478

  Fly   432 HMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRH 490
            ..|.|.||||.|::|:.|.|.|:.|.....|.|.||||:||:|..|...:.|::.|..|
  Rat   479 AQHQRIHTGEKPYECNICGKAFSYSGSLTLHQRIHTGERPYECKDCRKSFRQRAHLAHH 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	147/418 (35%)
		C2H2 Zn finger	84..104	CDD:275368	8/34 (24%)
		C2H2 Zn finger	112..132	CDD:275368	3/19 (16%)
		C2H2 Zn finger	139..159	CDD:275368	9/19 (47%)
		C2H2 Zn finger	167..187	CDD:275368	6/19 (32%)
		C2H2 Zn finger	195..215	CDD:275368	10/19 (53%)
		C2H2 Zn finger	223..243	CDD:275368	4/19 (21%)
		C2H2 Zn finger	250..270	CDD:275368	4/19 (21%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	10/19 (53%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Zfp583	NP_001128081.2	KRAB	6..66	CDD:214630
		COG5048	212..541	CDD:227381	137/353 (39%)
		C2H2 Zn finger	213..233	CDD:275368	9/19 (47%)
		C2H2 Zn finger	241..261	CDD:275368	6/19 (32%)
		C2H2 Zn finger	269..289	CDD:275368	10/19 (53%)
		C2H2 Zn finger	297..317	CDD:275368	8/46 (17%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	353..373	CDD:275368	7/19 (37%)
		C2H2 Zn finger	381..401	CDD:275368	10/19 (53%)
		C2H2 Zn finger	409..429	CDD:275368	6/19 (32%)
		C2H2 Zn finger	437..457	CDD:275368	8/19 (42%)
		C2H2 Zn finger	465..485	CDD:275368	6/19 (32%)
		C2H2 Zn finger	493..513	CDD:275368	7/19 (37%)
		C2H2 Zn finger	521..541	CDD:275368	5/17 (29%)