Protein Alignment CG5245 and Zfp141

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001296317.1
• Gene: Zfp141 / 434178
• MGIID: 3584269
• Length: 685
• Species: Mus musculus
• Alignment Length: 563
• Identity: 181/563 - (32%)
• Similarity: 263/563 - (46%)
• Gaps: 79/563 - (14%)

  Fly     1 MDLANVDQRPVKDEPP------------------QED----TFEEELIFISNSDFEELESEIKIE 43
            || .||||.....|.|                  |||    |.:..|....||.|.|:..:.. :
Mouse   128 MD-CNVDQHKTVYENPVGRESHHWLGISEYCHRYQEDNKGLTTDFALHNNHNSQFTEISYQGN-D 190

  Fly    44 NFCSYGKDLEPVKGVPS--KLKTCKSKIAKKRPLRKQTDTFKCTQC---QKTFTRKENLESHLRL 103
            ::..|.:|:.|.:|..|  .|:.|.:..      |.:..:.:|||.   |:.:::::...|..:.
Mouse   191 SWNIYKQDVTPSEGQISNCSLENCYNND------RCRGVSGQCTQSPLYQQDYSQEKLSTSSQQY 249

  Fly   104 HAEERPFECSHCSKSFGRRTHYKRHLLKHEK------------------RPHKCSHCSKTFTQNS 150
            ........||.|::...||...::...|:.|                  :|.......|:|....
Mouse   250 KIANECSNCSQCTEIKARREFNRQRYDKYSKVSVESPSIDRDKVNDIQRKPCLFMGSDKSFNFYL 314

  Fly   151 SLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEER------------------------ 191
            ::.|:...||.|:|.|..:........|.|..|.|:..:::
Mouse   315 NMTQNDSSHTREKPQKYKEYRLEITSPSKLVGHPRSFVQQKYRKSGKCSRSSSDLSRLKMLQPGG 379

  Fly   192 -PFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCP 254
             |.:.|.|.|:|...|..:|:...|...:|:||..|.:||...|.||.|...| .|:.:||.:|.
Mouse   380 TPCKSTECGKSFSQFSGYRENGTIHTGEKPYKCKICKRSFTTGSYLQAHQRIHTGEKPYKCKECG 444

  Fly   255 KTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLY 319
            |:|....||:||.|.|.||.|:||..|..:||..|.|:.|...|.|::|.||.:|..:||.:|.:
Mouse   445 KSFTHGYSLRIHHRFHTGEKPYKCKDCGRSFAEGSSLKSHHRIHTGEKPYKCKECGKSFAKQSNF 509

  Fly   320 RVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIG 384
            ..|.|:||.:|.|||.:|.|||.:...|.:|.:.||||:.:||..|.|.|..|:.|:.|...|.|
Mouse   510 ETHSRIHTGDRPYKCTDCGKSFTRSFCLRKHHKTHTGEKAYKCEECGKAFTQRSTLKTHYRIHTG 574

  Fly   385 EKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHC 449
            ||..||:.|.|.|...|.|..||:.|||:..::|..|.||:..:|||..|.|.||||.|:||:.|
Mouse   575 EKPYKCNECGKSFTEGSTLKTHLKIHTGEKPYKCKECGKSFAEASTLKTHHRIHTGEKPYKCTDC 639

  Fly   450 SKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            .|.|.:|:..|.|.|.|||||||||..|...:.:.|||.:|.|
Mouse   640 GKSFTQSSHLQSHCRIHTGEKPYKCKECGKSFAKDSSLQKHHR 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	151/450 (34%)
		C2H2 Zn finger	84..104	CDD:275368	5/22 (23%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	3/19 (16%)
		C2H2 Zn finger	167..187	CDD:275368	4/19 (21%)
		C2H2 Zn finger	195..215	CDD:275368	6/19 (32%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	7/19 (37%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	9/19 (47%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)
Zfp141	NP_001296317.1	KRAB	18..78	CDD:214630
		C2H2 Zn finger	385..404	CDD:275368	6/18 (33%)
		C2H2 Zn finger	412..432	CDD:275368	8/19 (42%)
		zf-H2C2_2	424..449	CDD:463886	10/24 (42%)
		C2H2 Zn finger	440..460	CDD:275368	9/19 (47%)
		COG5048	<445..685	CDD:227381	108/238 (45%)
		C2H2 Zn finger	468..488	CDD:275368	7/19 (37%)
		C2H2 Zn finger	496..516	CDD:275368	7/19 (37%)
		C2H2 Zn finger	524..544	CDD:275368	7/19 (37%)
		C2H2 Zn finger	552..572	CDD:275368	7/19 (37%)
		C2H2 Zn finger	580..600	CDD:275368	8/19 (42%)
		C2H2 Zn finger	608..628	CDD:275368	9/19 (47%)
		C2H2 Zn finger	636..656	CDD:275368	8/19 (42%)
		C2H2 Zn finger	664..684	CDD:275368	7/19 (37%)