Protein Alignment CG5245 and Zfp708

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001012325.2
• Gene: Zfp708 / 432769
• MGIID: 3040674
• Length: 541
• Species: Mus musculus
• Alignment Length: 516
• Identity: 174/516 - (33%)
• Similarity: 258/516 - (50%)
• Gaps: 43/516 - (8%)

  Fly    20 TFEEELIFISNSDFEELES-------EIKIEN------------------FCSYGKDLEPVK--- 56
            :|.:..|..|..:.|.|:|       |:.:||                  |.....||..||
Mouse    18 SFTDVAIDFSADECECLDSAQWNLYKEVMLENYSNLVFLGLAFSKPYLVTFLEQSSDLWSVKRKA 82

  Fly    57 ----GVPSKLKTCK---------SKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEER 108
                .:.||...||         |.:.:.:.:......:||.:|...||.:..|..|.|:|..|:
Mouse    83 SVAIHLGSKAHKCKECGKSFDRNSVLIQHQRIHTGERPYKCEECGMAFTGRCILSKHQRIHTGEK 147

  Fly   109 PFECSHCSKSFGRRTHYKRHLLKH-EKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCST 172
            |::|..|.|:|...::..:|...| |::|:||..|.|.|:.:|.|.:|...|||.:|:||.:|..
Mouse   148 PYKCKECGKAFSCSSNLHQHQQIHREEKPYKCDDCGKAFSCSSYLYKHQRIHTGMKPYKCKECGK 212

  Fly   173 SFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSF-KLRSIL 236
            :|...::|..|.|.|:.|:|::|..|.|||...|....|.|||...:|::|..|.|:| ...:::
Mouse   213 AFNCSANLIYHQRIHTGEKPYKCGECGKAFTIYSTFMNHQRTHSGEKPYECKDCGKAFTNCYNLI 277

  Fly   237 QKHLLTHAERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGK 301
            |...:...|:.:.|.:|.|:|..:..|:.|.|:|.||.|:||..|.:.|..:..|..|...|.|:
Mouse   278 QHQRIHTGEKPYACEECGKSFNYSSHLKQHKRIHTGEKPYKCEVCGKAFNCSDYLVKHQRIHTGE 342

  Fly   302 EPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCF 366
            :|.||..|...|:..:....|.|:||.|::|:|.||.|:|...|.|:.|::|||||:|:||..|.
Mouse   343 KPYKCEVCGKAFSFSTYLHKHQRIHTGEKRYRCEECGKAFTNYSGLIVHRRVHTGEKPYKCEECG 407

  Fly   367 KDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTL 431
            |.|...|.|..|...|..|:..||..|.|.|.:.|....|...||.:..::|.||.|::...|.|
Mouse   408 KAFSVHTSLSKHQRIHTREQPYKCDECGKTFSVHSTFSKHQIMHTREKPYKCKHCDKTFKYPSPL 472

  Fly   432 HMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            ..|.|.||||.|:||..|.|.|..|:..:.|.|.|||||||||..|...:...|::.||.:
Mouse   473 VQHERIHTGERPYKCEVCGKAFTSSSNLKYHWRLHTGEKPYKCEQCGKAFKNSSNVTRHYK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	151/405 (37%)
		C2H2 Zn finger	84..104	CDD:275368	7/19 (37%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	6/19 (32%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	5/20 (25%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Zfp708	NP_001012325.2	KRAB	17..77	CDD:214630	12/58 (21%)
		C2H2 Zn finger	95..115	CDD:275368	3/19 (16%)
		COG5048	119..540	CDD:227381	155/415 (37%)
		C2H2 Zn finger	123..143	CDD:275368	7/19 (37%)
		C2H2 Zn finger	151..171	CDD:275368	5/19 (26%)
		C2H2 Zn finger	179..199	CDD:275368	7/19 (37%)
		C2H2 Zn finger	207..227	CDD:275368	6/19 (32%)
		C2H2 Zn finger	235..255	CDD:275368	8/19 (42%)
		C2H2 Zn finger	263..283	CDD:275368	5/19 (26%)
		C2H2 Zn finger	291..311	CDD:275368	7/19 (37%)
		C2H2 Zn finger	319..339	CDD:275368	5/19 (26%)
		C2H2 Zn finger	347..367	CDD:275368	5/19 (26%)
		C2H2 Zn finger	375..395	CDD:275368	8/19 (42%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		C2H2 Zn finger	431..451	CDD:275368	6/19 (32%)
		C2H2 Zn finger	459..479	CDD:275368	8/19 (42%)
		C2H2 Zn finger	487..507	CDD:275368	7/19 (37%)
		C2H2 Zn finger	515..535	CDD:275368	5/19 (26%)