Protein Alignment CG5245 and Zfp950

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001296145.1
• Gene: Zfp950 / 414758
• MGIID: 2652824
• Length: 609
• Species: Mus musculus
• Alignment Length: 484
• Identity: 186/484 - (38%)
• Similarity: 287/484 - (59%)
• Gaps: 22/484 - (4%)

  Fly    22 EEELIFISNSDFEELESEIKIENF-----CSYGKDLEPVKGVPSKLKTCKSKIAKKRPLRKQTD- 80
            :||...:.:|. :.|..::.:|.:     ..|..|...::      :.|:|   .:|..|.:|.
Mouse    15 QEEWALLDHSQ-KSLYRDVMLETYKNLTAIGYNWDDHNIE------EHCQS---SRRHGRHETSH 69

  Fly    81 ----TFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHE-KRPHKCS 140
                ..:.|.|.|.|....:.:.|.|:|..|:|:.|:||.|:|...::.:||...|. ::|::|:
Mouse    70 PGEKPSQYTHCGKAFVYWSHPQRHERIHTGEKPYGCNHCGKAFAHHSNLQRHERIHTGEKPYECN 134

  Fly   141 HCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNN 205
            .|.|.|..:|.|:.|...||||:|::|.||..:||..|:||.|.|.|:.|:|:||..|.|||..:
Mouse   135 QCGKAFVTHSDLQIHKRTHTGEKPYECNQCGKAFAYHSNLQRHERIHTGEKPYECNQCGKAFAYH 199

  Fly   206 SHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRV 269
            |:||.|.|.|...:|::|:.|.|:|...|.||:|.:|| .|:.::|.||.|.|..:.:|.||.|.
Mouse   200 SNLQRHERIHTGEKPYECNKCGKAFAWHSHLQRHEITHTGEKPYECNQCGKAFAHDSNLHIHKRK 264

  Fly   270 HAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKC 334
            ||||.|::|..|.:.|...:.||:|...|.|::|.:|:||..|||..|..::|.|:||.|:.|:|
Mouse   265 HAGEKPYECNQCGKAFPCYNLLQIHKRTHTGEKPYECNQCGKTFAYHSYLQMHERIHTGEKPYEC 329

  Fly   335 AECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKL 399
            ..|.|:|.:.|.|..|::.||||:|::|..|.:.|...:||::|...|.|||..:|:.|.|.|..
Mouse   330 NHCGKAFSQHSSLRVHKRTHTGEKPYECNQCGEAFVYHSHLQIHKTMHTGEKPFQCNQCDKAFVY 394

  Fly   400 SSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLR 464
            ::.||||.:.|||:..:||.||.|:::..|.||:|.||||||.|:||:.|.|.|||::..|.|.|
Mouse   395 NNHLLVHKRIHTGEKPYECNHCGKAFSQLSGLHVHKRTHTGEKPYKCNECGKAFARNSHLQRHKR 459

  Fly   465 THTGEKPYKCSHCSTRYTQKSSLGRHLRR 493
            .||||||::|:.|...:.:.|:|..|.|:
Mouse   460 IHTGEKPHECNQCGKAFARHSTLQVHKRK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	171/410 (42%)
		C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		C2H2 Zn finger	112..132	CDD:275368	7/19 (37%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	10/19 (53%)
		C2H2 Zn finger	195..215	CDD:275368	10/19 (53%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	9/19 (47%)
		C2H2 Zn finger	334..354	CDD:275368	7/19 (37%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	9/19 (47%)
		C2H2 Zn finger	446..466	CDD:275368	9/19 (47%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Zfp950	NP_001296145.1	KRAB	4..44	CDD:460171	5/29 (17%)
		C2H2 Zn finger	78..97	CDD:275368	6/18 (33%)
		COG5048	101..514	CDD:227381	166/388 (43%)
		C2H2 Zn finger	105..125	CDD:275368	7/19 (37%)
		C2H2 Zn finger	133..153	CDD:275368	7/19 (37%)
		C2H2 Zn finger	161..181	CDD:275368	10/19 (53%)
		C2H2 Zn finger	189..209	CDD:275368	10/19 (53%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	245..265	CDD:275368	9/19 (47%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		C2H2 Zn finger	301..321	CDD:275368	9/19 (47%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		C2H2 Zn finger	413..433	CDD:275368	9/19 (47%)
		C2H2 Zn finger	441..461	CDD:275368	9/19 (47%)
		C2H2 Zn finger	469..489	CDD:275368	6/20 (30%)
		C2H2 Zn finger	497..517	CDD:275368
		C2H2 Zn finger	525..545	CDD:275368
		C2H2 Zn finger	553..573	CDD:275368
		C2H2 Zn finger	581..601	CDD:275368