Protein Alignment CG5245 and ZNF790

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_047294754.1
• Gene: ZNF790 / 388536
• HGNCID: 33114
• Length: 670
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 147/480 - (30%)
• Similarity: 221/480 - (46%)
• Gaps: 79/480 - (16%)

  Fly    27 FISNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTC------KSKIAKKRPLRKQTDTFKCT 85
            |||.||..:.:.....|.||..              |.|      .|::.:.:.:.....|::|.
Human   213 FISGSDHTQHQLIHTSEKFCGD--------------KECGNTFLPDSEVIQYQTVHTVKKTYECK 263

  Fly    86 QCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHE-KRPHKCSHCSKTFTQN 149
            :|.|:|:.:.:|..|.|:|..|:||:|..|.|:|...:....|...|. ::.::|..|.|.|:..
Human   264 ECGKSFSLRSSLTGHKRIHTGEKPFKCKDCGKAFRFHSQLSVHKRIHTGEKSYECKECGKAFSCG 328

  Fly   150 SSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRT 214
            |.|.:|...||||:|::|.:|..:|:::|||..|.|.|:.|:|:||..|.|||...|||.:|.|.
Human   329 SDLTRHQRIHTGEKPYECNECRKAFSQRSHLIKHQRIHTGEKPYECKECGKAFTRGSHLTQHQRI 393

  Fly   215 HQEARPFKCSHCSKSFKLRSILQKHLLTHAERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCP 279
            |.                           .|:|.:|.:|.|.|::..:|..|..||.|..|:||.
Human   394 HT---------------------------GEKSHECKECGKAFIRGSNLAQHQNVHVGRKPYKCE 431

  Fly   280 HCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKK 344
            .|.:.:..:|.|..|...|.|::|.:|.||..||...|....|.::|...:.|:|.||.|:|...
Human   432 KCGKAYIWSSHLARHQRIHTGRKPYECKQCGKTFTWASYLAQHEKIHNERKSYECKECGKTFLHG 496

  Fly   345 SHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQE 409
            |....||::|||||.::|..|.|.|                           |: .|:|..|.:.
Human   497 SEFNRHQKIHTGERNYECKECGKTF---------------------------FR-GSELNRHQKI 533

  Fly   410 HTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKC 474
            ||||..:||..|.|::...|.|..|.|.||||.|:.|..|.|.|...::...|.:.||..:||.|
Human   534 HTGKRPYECEECGKAFLWGSQLTRHQRMHTGEEPYVCKECGKSFIWGSQLTRHKKIHTDAEPYGC 598

  Fly   475 ---SHCSTRYTQKSSLGRHLRRTLC 496
               ||..:.::..:....|....||
Human   599 KKSSHIFSHHSYFTEQKIHNSANLC 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	133/407 (33%)
		C2H2 Zn finger	84..104	CDD:275368	7/19 (37%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	10/19 (53%)
		C2H2 Zn finger	223..243	CDD:275368	0/19 (0%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	4/19 (21%)
		C2H2 Zn finger	390..410	CDD:275368	4/19 (21%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	5/19 (26%)
		C2H2 Zn finger	474..492	CDD:275368	4/20 (20%)
ZNF790	XP_047294754.1	KRAB	39..98	CDD:214630
		C2H2 Zn finger	179..198	CDD:275368
		C2H2 Zn finger	206..226	CDD:275368	5/12 (42%)
		C2H2 Zn finger	235..254	CDD:275368	3/18 (17%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		zf-H2C2_2	278..297	CDD:463886	9/18 (50%)
		C2H2 Zn finger	290..310	CDD:275368	5/19 (26%)
		zf-H2C2_2	303..327	CDD:463886	6/23 (26%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		COG5048	342..>609	CDD:227381	104/321 (32%)
		C2H2 Zn finger	346..366	CDD:275368	8/19 (42%)
		C2H2 Zn finger	374..394	CDD:275368	10/19 (53%)
		C2H2 Zn finger	402..422	CDD:275368	6/19 (32%)
		C2H2 Zn finger	430..450	CDD:275368	5/19 (26%)
		C2H2 Zn finger	458..478	CDD:275368	7/19 (37%)
		C2H2 Zn finger	486..506	CDD:275368	8/19 (42%)
		C2H2 Zn finger	514..534	CDD:275368	8/47 (17%)
		C2H2 Zn finger	542..562	CDD:275368	7/19 (37%)
		C2H2 Zn finger	570..590	CDD:275368	5/19 (26%)
		C2H2 Zn finger	598..617	CDD:275368	3/18 (17%)