Protein Alignment CG5245 and Gm5141

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001242994.1
• Gene: Gm5141 / 380850
• MGIID: 3779466
• Length: 581
• Species: Mus musculus
• Alignment Length: 474
• Identity: 177/474 - (37%)
• Similarity: 270/474 - (56%)
• Gaps: 16/474 - (3%)

  Fly    34 EELESEI--KIENFCSYGKDLEPVKGVPSKLK-----------TCKSKIAKKRPLRKQTDTFKCT 85
            |::.||:  .||:|..| ..|:..|...:..|           .|.|.:.:...:......:||.
Mouse   101 EKIPSEVIHCIEDFLPY-TSLQVHKRAQTGQKQYEYKQCGKGFACPSLLKRHERIHTVEKPYKCN 164

  Fly    86 QCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKH-EKRPHKCSHCSKTFTQN 149
            ||.|.|:.|.:|:.|:|.|..|:||:|:.|.|:|....:.:.|...| .::|.||:.|.|.|:|.
Mouse   165 QCDKAFSLKYSLQRHIRTHTGEKPFKCNQCEKAFSHHCNLQTHRRTHTREKPFKCNECDKAFSQF 229

  Fly   150 SSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRT 214
            .:|:.|...||||:||||.:|..:|:.|..||.|:..|:.|:|::|..|:|||.:...|..|:|.
Mouse   230 GNLQNHRRTHTGEKPFKCNECDKAFSEKGSLQKHISIHTGEKPYKCNQCDKAFSHKQSLLIHIRI 294

  Fly   215 HQEARPFKCSHCSKSFKLRSILQKHLLTHA-ERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKC 278
            |...:|:||:.|.|:|..:.||:.|:..|: |:.:||..|.|.|.::..||.|:|.|.||.|::|
Mouse   295 HTGEKPYKCNQCDKAFSHKHILKNHIRIHSGEKPYKCNLCDKVFSRHFHLQNHIRTHTGEKPYRC 359

  Fly   279 PHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFK 343
            ..|.:.|:.:..||.|...|.|::|.||::|...|:.:...:.|:|.||.|:.|||.:|.|:|..
Mouse   360 NQCDKAFSHHKTLQTHRKTHTGEKPFKCNECDKAFSEKGSLQSHIRTHTGEKPYKCNQCDKAFSH 424

  Fly   344 KSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQ 408
            |.:|..|.::||||:|:||..|.|.|..:.:|::|:..|.|||..||:.|.|.|.....|..|.:
Mouse   425 KQNLQIHIRIHTGEKPYKCNQCDKAFSYKQNLQIHIRIHTGEKPYKCNQCDKAFLHQGNLQTHRR 489

  Fly   409 EHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYK 473
            .||....|:|..|.|.::....|..|:||||.|.|:||:.|.|.|::.:..|.|.||||||||:|
Mouse   490 THTRDKPFQCNLCDKVFSRHFHLQNHIRTHTREKPYKCNECGKGFSQHSSLQTHRRTHTGEKPFK 554

  Fly   474 CSHCSTRYTQKSSLGRHLR 492
            |:.|...::.|..|..|:|
Mouse   555 CNQCDKAFSCKHHLQTHIR 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	160/405 (40%)
		C2H2 Zn finger	84..104	CDD:275368	9/19 (47%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	7/19 (37%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
		C2H2 Zn finger	334..354	CDD:275368	7/19 (37%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Gm5141	NP_001242994.1	KRAB	4..44	CDD:460171
		C2H2 Zn finger	136..155	CDD:275368	2/18 (11%)
		zf-H2C2_2	148..171	CDD:463886	5/22 (23%)
		C2H2 Zn finger	163..183	CDD:275368	9/19 (47%)
		COG5048	187..566	CDD:227381	149/378 (39%)
		C2H2 Zn finger	191..211	CDD:275368	5/19 (26%)
		C2H2 Zn finger	219..239	CDD:275368	7/19 (37%)
		C2H2 Zn finger	247..267	CDD:275368	7/19 (37%)
		C2H2 Zn finger	275..295	CDD:275368	8/19 (42%)
		C2H2 Zn finger	303..323	CDD:275368	7/19 (37%)
		C2H2 Zn finger	331..351	CDD:275368	8/19 (42%)
		C2H2 Zn finger	359..379	CDD:275368	6/19 (32%)
		C2H2 Zn finger	387..407	CDD:275368	5/19 (26%)
		C2H2 Zn finger	415..435	CDD:275368	7/19 (37%)
		C2H2 Zn finger	443..463	CDD:275368	6/19 (32%)
		C2H2 Zn finger	471..491	CDD:275368	6/19 (32%)
		C2H2 Zn finger	499..519	CDD:275368	6/19 (32%)
		C2H2 Zn finger	527..547	CDD:275368	7/19 (37%)
		C2H2 Zn finger	555..575	CDD:275368	6/19 (32%)