Protein Alignment CG5245 and Zfp53

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001100938.1
• Gene: Zfp53 / 308236
• RGDID: 1308573
• Length: 631
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 193/490 - (39%)
• Similarity: 269/490 - (54%)
• Gaps: 35/490 - (7%)

  Fly    13 DEPPQEDTFEEELIFISN--SDFEELESEIKIENFCS-YGKDLEPVKGVPSKLKTCKSKIAKKRP 74
            :||.:....|:.....||  .|..:|:|:.|.:.|.| |.
  Rat   159 EEPCESKNCEKSFNLCSNISQDANKLQSQGKYDEFSSAYS------------------------- 198

  Fly    75 LRKQT----DT-FKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHE- 133
            |.:||    || .:|.:|:|.|:...:|..|.|:|..::|::|:.|.|||.:.|:.|.|...|.
  Rat   199 LMQQTIYIGDTPHQCEKCRKCFSTASSLTVHQRIHTGKKPYKCNVCHKSFTQCTNLKTHQRLHTG 263

  Fly   134 KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHC 198
            ::|:||..|.|:|.|.|:||.|...||||||:||.:|..|||..|..:.|.:.||.|..:.|..|
  Rat   264 EKPYKCKDCGKSFPQLSALKSHQKMHTGERPYKCKECDKSFAHCSSFRRHQKIHSAEEYYTCQQC 328

  Fly   199 EKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTHA-ERSFKCTQCPKTFLQNDS 262
            .|.....|||:.|.|.|...:|:|||.|.:||...:..::|..||: |:.:||.:|.|:||:...
  Rat   329 GKVLHQLSHLRSHHRLHTGEKPYKCSECDRSFTHYASYRRHQKTHSLEKFYKCKECGKSFLELSH 393

  Fly   263 LQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHT 327
            |:.|.|:|.||.|:||..|.::|..||.|:.|...|.|::|.||.:|..:|...|..|.|..:||
  Rat   394 LKRHYRIHTGEKPYKCEVCDKSFTVNSTLKTHQKIHTGEKPFKCRECDKSFTKCSHLRRHQSVHT 458

  Fly   328 RERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSY 392
            .||.|||.||.|||.:.|.|..||::||||:|:||..|.|.|..|::||:|...|.||:...|..
  Rat   459 GERPYKCKECDKSFTECSTLRAHQKIHTGEKPYKCRECNKSFIQRSNLRIHQRVHTGERPYVCKE 523

  Fly   393 CSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSA 457
            |.|.|...|.|..|.:.|||:..::|..|:||:|..|.|..|.|.||||.|:.|..|.|.|.|.:
  Rat   524 CGKSFTKCSTLQTHQKIHTGEKPYKCRECNKSFTQDSHLRTHQRVHTGERPYICKECGKSFTRCS 588

  Fly   458 EHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            ..:.|.:.|||||||||..|...:.|.|:|.||.|
  Rat   589 YLRAHQKIHTGEKPYKCKDCDVSFMQISNLRRHQR 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	174/410 (42%)
		C2H2 Zn finger	84..104	CDD:275368	7/19 (37%)
		C2H2 Zn finger	112..132	CDD:275368	8/19 (42%)
		C2H2 Zn finger	139..159	CDD:275368	9/19 (47%)
		C2H2 Zn finger	167..187	CDD:275368	7/19 (37%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	6/19 (32%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	10/19 (53%)
		C2H2 Zn finger	362..382	CDD:275368	8/19 (42%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	9/19 (47%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..492	CDD:275368	7/17 (41%)
Zfp53	NP_001100938.1	KRAB	44..84	CDD:460171
		COG5048	208..614	CDD:227381	172/405 (42%)
		C2H2 Zn finger	213..233	CDD:275368	7/19 (37%)
		C2H2 Zn finger	241..261	CDD:275368	8/19 (42%)
		C2H2 Zn finger	269..289	CDD:275368	9/19 (47%)
		C2H2 Zn finger	297..317	CDD:275368	7/19 (37%)
		C2H2 Zn finger	353..373	CDD:275368	6/19 (32%)
		C2H2 Zn finger	381..401	CDD:275368	8/19 (42%)
		C2H2 Zn finger	409..429	CDD:275368	7/19 (37%)
		C2H2 Zn finger	437..457	CDD:275368	6/19 (32%)
		C2H2 Zn finger	465..485	CDD:275368	10/19 (53%)
		C2H2 Zn finger	493..513	CDD:275368	8/19 (42%)
		C2H2 Zn finger	521..541	CDD:275368	7/19 (37%)
		C2H2 Zn finger	549..569	CDD:275368	9/19 (47%)
		C2H2 Zn finger	577..597	CDD:275368	6/19 (32%)
		C2H2 Zn finger	605..625	CDD:275368	8/19 (42%)