Protein Alignment CG5245 and Rbak

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001178593.1
• Gene: Rbak / 288489
• RGDID: 1562875
• Length: 711
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 172/502 - (34%)
• Similarity: 257/502 - (51%)
• Gaps: 66/502 - (13%)

  Fly    29 SNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCKSKIAKKRPLRKQTDTFKCTQCQKTFTR 93
            |..||      |:|.:|.:|.                :|::..|        .|:||||.|:|.:
  Rat   235 SGPDF------IQISDFSTYH----------------RSQVEMK--------PFECTQCGKSFCK 269

  Fly    94 KENLESHLRLHAEERPFECSHCSKSFGRR----THYKRHLLKHEKRPHKCSHCSKTFTQNSSLKQ 154
            |.....|.|.|..|:|:.|..|.|||.::    .|.:.||   |::|:||..|.|||.|...|.|
  Rat   270 KSKFIIHQRAHTGEKPYACGVCGKSFSQKGTLTVHRRSHL---EEKPYKCDECGKTFCQKLHLTQ 331

  Fly   155 HLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEAR 219
            |...|:||:|::|::|..:|.:|:||.:|.|.||.|||:.|:.|.|:|...|.|.:|.|||...:
  Rat   332 HQRTHSGEKPYECSECGKTFCQKTHLTLHQRNHSGERPYPCSECGKSFSRKSALNDHQRTHTGEK 396

  Fly   220 PFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSE 283
            .:.|:.|.||:..:|.|..|..|| .|:.::|::|.|.|.:...|.||.|.|..|.|::|..|.:
  Rat   397 LYTCNECGKSYYRKSTLITHQRTHTGEKPYQCSECGKFFSRVSYLTIHYRSHLEEKPYECTECGK 461

  Fly   284 TFARN------------------------SRLQLHLLEHA---GKEPLKCSQCSATFAMRSLYRV 321
            ||..|                        |||| :|.:||   |::...|::|..||...|.:..
  Rat   462 TFNLNSAFTRHRKAHAEERVQECGECGKPSRLQ-YLPDHADGLGEKHHGCNECGKTFLENSAFSR 525

  Fly   322 HVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEK 386
            |..:...|:.|:|..|.|.|...|....|.:.|:.|:||.|:.|.|.|...:.|..|...|.|||
  Rat   526 HQPVPEGEKTYECNICGKVFSDLSCYTVHYRGHSEEKPFGCSECGKTFSHNSSLFRHQRVHTGEK 590

  Fly   387 VPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSK 451
            ..:|..|.|.|...|.|.:|.:.|:|:..:||..|.|.::..|.|.:|.|:|:||.|::|:.|.|
  Rat   591 PYECYECGKFFSQKSYLTIHHRIHSGEKPYECSKCGKVFSRMSNLTVHYRSHSGEKPYECNECGK 655

  Fly   452 LFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLRRTLCGT 498
            :|::.:....|.|||:|||||:|:.|..::..:|:...|.|....||
  Rat   656 VFSQKSYLTVHYRTHSGEKPYECNECGKKFHHRSAFNSHQRIHKRGT 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	157/435 (36%)
		C2H2 Zn finger	84..104	CDD:275368	9/19 (47%)
		C2H2 Zn finger	112..132	CDD:275368	8/23 (35%)
		C2H2 Zn finger	139..159	CDD:275368	9/19 (47%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		C2H2 Zn finger	278..298	CDD:275368	10/43 (23%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	6/19 (32%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..492	CDD:275368	4/17 (24%)
Rbak	NP_001178593.1	KRAB	8..68	CDD:214630
		C2H2 Zn finger	260..280	CDD:275368	9/19 (47%)
		C2H2 Zn finger	288..308	CDD:275368	6/19 (32%)
		zf-C2H2	314..336	CDD:395048	10/21 (48%)
		C2H2 Zn finger	316..336	CDD:275368	9/19 (47%)
		COG5048	340..699	CDD:227381	125/359 (35%)
		C2H2 Zn finger	344..364	CDD:275368	8/19 (42%)
		C2H2 Zn finger	372..392	CDD:275368	8/19 (42%)
		C2H2 Zn finger	400..420	CDD:275368	7/19 (37%)
		C2H2 Zn finger	428..448	CDD:275368	8/19 (42%)
		C2H2 Zn finger	456..476	CDD:275368	5/19 (26%)
		C2H2 Zn finger	510..530	CDD:275368	6/19 (32%)
		C2H2 Zn finger	538..558	CDD:275368	6/19 (32%)
		C2H2 Zn finger	566..586	CDD:275368	6/19 (32%)
		C2H2 Zn finger	594..614	CDD:275368	7/19 (37%)
		C2H2 Zn finger	622..642	CDD:275368	7/19 (37%)
		C2H2 Zn finger	650..670	CDD:275368	6/19 (32%)
		C2H2 Zn finger	678..698	CDD:275368	5/19 (26%)