DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5245 and Zfp689

DIOPT Version :10

Sequence 1:NP_650197.1 Gene:CG5245 / 41530 FlyBaseID:FBgn0038047 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_775452.1 Gene:Zfp689 / 286996 RGDID:628696 Length:500 Species:Rattus norvegicus


Alignment Length:442 Identity:136/442 - (30%)
Similarity:191/442 - (43%) Gaps:84/442 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 KDLEPVKGVPSKLKTCKSKIAKKRPLRKQTDTFK-CTQCQKTFTRKENLESHLRLHAEERPFECS 113
            |::.|.|.||.|.|..: |.:|.|.:.:||.... |..|..||.....||||             
  Rat   117 KEVFPPKDVPRKGKRGR-KPSKPRLIARQTSGGPICPDCGCTFPDLPALESH------------- 167

  Fly   114 HCSKSFGRRTHYKRHLLKHEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKS 178
            .|:::.              |:|:.|..|.:.|:..|.|..|...|:||.|:.|.||...|:::.
  Rat   168 KCAQNL--------------KKPYPCPDCGRRFSYPSLLVSHRRAHSGECPYVCDQCGKRFSQRK 218

  Fly   179 HLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH 243
            :|..|...|:.|:|:.|..|.:.|:.:..|..|..|                             
  Rat   219 NLSQHQVIHTGEKPYHCPDCGRCFRRSRSLANHRTT----------------------------- 254

  Fly   244 AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQ 308
                                      |.||.|.:||.|...||..|.|.:|...|.|::|..|.:
  Rat   255 --------------------------HTGEKPHQCPSCGRRFAYPSLLAIHQRTHTGEKPYTCLE 293

  Fly   309 CSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRT 373
            ||..|..|:...:|.|:||.|:.|.|.:|.:.|...|.||.|::||:||||:.|.||...|..|:
  Rat   294 CSRRFRQRTALVIHQRIHTGEKPYPCPDCERRFSSSSRLVSHRRVHSGERPYACEHCEARFSQRS 358

  Fly   374 HLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTH 438
            .|..|.|.|.|||...|..|.:.|:.|..|.:|...||.:....|..|.:.:...|.|..|.|.|
  Rat   359 TLLQHQLLHTGEKPYPCPDCGRAFRRSGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASHRRVH 423

  Fly   439 TGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRH 490
            :||.|:.|..|||.||:.:...:|...||||||:.|..|...:.|:.||..|
  Rat   424 SGERPYACDLCSKRFAQWSHLAQHQLLHTGEKPFPCLECGRCFRQRWSLAVH 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5245NP_650197.1 COG5048 74..478 CDD:227381 121/404 (30%)
C2H2 Zn finger 84..104 CDD:275368 8/19 (42%)
C2H2 Zn finger 112..132 CDD:275368 1/19 (5%)
C2H2 Zn finger 139..159 CDD:275368 6/19 (32%)
C2H2 Zn finger 167..187 CDD:275368 6/19 (32%)
C2H2 Zn finger 195..215 CDD:275368 5/19 (26%)
C2H2 Zn finger 223..243 CDD:275368 0/19 (0%)
C2H2 Zn finger 250..270 CDD:275368 0/19 (0%)
C2H2 Zn finger 278..298 CDD:275368 8/19 (42%)
C2H2 Zn finger 306..326 CDD:275368 7/19 (37%)
C2H2 Zn finger 334..354 CDD:275368 7/19 (37%)
C2H2 Zn finger 362..382 CDD:275368 8/19 (42%)
C2H2 Zn finger 390..410 CDD:275368 6/19 (32%)
C2H2 Zn finger 418..438 CDD:275368 6/19 (32%)
C2H2 Zn finger 446..466 CDD:275368 7/19 (37%)
C2H2 Zn finger 474..492 CDD:275368 6/17 (35%)
Zfp689NP_775452.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
KRAB 29..88 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 110..144 10/27 (37%)
C2H2 Zn finger 151..171 CDD:275368 9/32 (28%)
COG5048 159..>466 CDD:227381 116/388 (30%)
C2H2 Zn finger 179..199 CDD:275368 6/19 (32%)
C2H2 Zn finger 207..227 CDD:275368 6/19 (32%)
C2H2 Zn finger 235..255 CDD:275368 6/74 (8%)
C2H2 Zn finger 263..283 CDD:275368 8/19 (42%)
C2H2 Zn finger 291..311 CDD:275368 7/19 (37%)
C2H2 Zn finger 319..339 CDD:275368 7/19 (37%)
C2H2 Zn finger 347..367 CDD:275368 8/19 (42%)
C2H2 Zn finger 375..395 CDD:275368 6/19 (32%)
C2H2 Zn finger 403..423 CDD:275368 6/19 (32%)
C2H2 Zn finger 431..451 CDD:275368 7/19 (37%)
C2H2 Zn finger 459..475 CDD:275368 5/15 (33%)
Blue background indicates that the domain is not in the aligned region.

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