DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5245 and Zfp260

DIOPT Version :9

Sequence 1:NP_650197.1 Gene:CG5245 / 41530 FlyBaseID:FBgn0038047 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_036111.2 Gene:Zfp260 / 26466 MGIID:1347071 Length:407 Species:Mus musculus


Alignment Length:391 Identity:140/391 - (35%)
Similarity:221/391 - (56%) Gaps:14/391 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 FKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHEKR-PHKCSHCSKT 145
            ::|.:|::||:.::|...|.:.|:.|:..||:.|.:...:.:....||....:| .:||..|.|.
Mouse    23 YECNECKETFSLEQNFVEHKKTHSGEKSPECTGCGEESSQASSLTLHLRSRPRRESYKCGECGKA 87

  Fly   146 FTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHL----QVHLRTHSEERPFECTHCEKAFKNNS 206
            |:|..:...|..:||.|||        |.::|:.:    .|..:.::..:|:.|..|.|||...|
Mouse    88 FSQRGNFLSHQKQHTEERP--------SESKKTPVPMTTTVRNQRNTGNKPYACKECGKAFNGKS 144

  Fly   207 HLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTHA-ERSFKCTQCPKTFLQNDSLQIHLRVH 270
            :|:||.:.|...:||:||.|.::|..:..|.||...|: ::.|||.:|.|.|.|.::|.||.|:|
Mouse   145 YLKEHEKIHTGEKPFECSQCGRAFSQKQYLIKHQNIHSGKKPFKCNECGKAFSQKENLIIHQRIH 209

  Fly   271 AGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCA 335
            .||.|::|..|.:.|.:.|.|..|...|.|::|..|.:|...|:.:|....|.::|..|:.|||.
Mouse   210 TGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCN 274

  Fly   336 ECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLS 400
            ||...|.:|.:|::|..:||||:|::|..|.|.|...|.|.||:..|.|:|..:|..|.|.|..|
Mouse   275 ECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKICGKAFCQS 339

  Fly   401 SQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRT 465
            |.|.||::.|||:..:.|..|.|:::..|||.:|:|.||||.|::||.|.|.|::.:.|..|.|.
Mouse   340 SSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRI 404

  Fly   466 H 466
            |
Mouse   405 H 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5245NP_650197.1 COG5048 74..478 CDD:227381 140/391 (36%)
C2H2 Zn finger 84..104 CDD:275368 6/19 (32%)
C2H2 Zn finger 112..132 CDD:275368 4/19 (21%)
C2H2 Zn finger 139..159 CDD:275368 6/19 (32%)
C2H2 Zn finger 167..187 CDD:275368 3/23 (13%)
zf-H2C2_2 179..204 CDD:290200 7/28 (25%)
C2H2 Zn finger 195..215 CDD:275368 9/19 (47%)
C2H2 Zn finger 223..243 CDD:275368 7/19 (37%)
C2H2 Zn finger 250..270 CDD:275368 9/19 (47%)
C2H2 Zn finger 278..298 CDD:275368 6/19 (32%)
C2H2 Zn finger 306..326 CDD:275368 5/19 (26%)
C2H2 Zn finger 334..354 CDD:275368 7/19 (37%)
C2H2 Zn finger 362..382 CDD:275368 8/19 (42%)
C2H2 Zn finger 390..410 CDD:275368 9/19 (47%)
C2H2 Zn finger 418..438 CDD:275368 8/19 (42%)
C2H2 Zn finger 446..466 CDD:275368 8/19 (42%)
C2H2 Zn finger 474..492 CDD:275368
Zfp260NP_036111.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
COG5048 22..401 CDD:227381 137/385 (36%)
C2H2 Zn finger 25..45 CDD:275368 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 39..72 8/32 (25%)
C2H2 Zn finger 53..73 CDD:275368 4/19 (21%)
C2H2 Zn finger 81..101 CDD:275368 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 96..124 9/35 (26%)
C2H2 Zn finger 133..153 CDD:275368 9/19 (47%)
C2H2 Zn finger 161..181 CDD:275368 7/19 (37%)
C2H2 Zn finger 189..209 CDD:275368 9/19 (47%)
C2H2 Zn finger 217..237 CDD:275368 6/19 (32%)
C2H2 Zn finger 245..265 CDD:275368 5/19 (26%)
C2H2 Zn finger 273..293 CDD:275368 7/19 (37%)
C2H2 Zn finger 301..321 CDD:275368 8/19 (42%)
C2H2 Zn finger 329..349 CDD:275368 9/19 (47%)
C2H2 Zn finger 357..377 CDD:275368 8/19 (42%)
C2H2 Zn finger 385..405 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100020
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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