Protein Alignment CG5245 and Zfp933

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_941021.1
• Gene: Zfp933 / 242747
• MGIID: 1922865
• Length: 468
• Species: Mus musculus
• Alignment Length: 488
• Identity: 175/488 - (35%)
• Similarity: 267/488 - (54%)
• Gaps: 47/488 - (9%)

  Fly    22 EEELIFISNSDFEELESEIKIENF-----CSYGKDLEPVKGVPSKLKTCKSKIAKKRPLRKQT-- 79
            :||.:.:..|. :.|..::.:|.:     ..|..:..|.:      :.|:|...:.|..|..|
Mouse    15 QEEWVLLDPSQ-KSLYKDVMLETYRNLSAIGYNWEAHPTE------EHCQSSRRRGRHERSPTGE 72

  Fly    80 DTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTH---YKRHLLKHEKRPHKCSH 141
            :.::|.:..|.|......:.|.|:|..|:|:|.....:.|...:.   |||  :...::|::|:.
Mouse    73 EPYECNKSGKAFAYHHYPQWHERIHTGEKPYEVIQYGEDFVYHSSLQIYKR--IAIGEKPYECNQ 135

  Fly   142 CSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNS 206
            |.|.||.:|.|::|...||||:|:||.||..:|::..||.:|.|||:.|:|:||..|.|||.:.|
Mouse   136 CGKAFTYHSQLRRHKRTHTGEKPYKCNQCDKAFSQNGHLIIHKRTHTGEKPYECNQCGKAFTDQS 200

  Fly   207 HLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTHAERSFKCTQCPKTFLQNDSLQIHLRVHA 271
            .|:.|.|.|...:|:||:                           ||.|.||||.:|:||.|.|.
Mouse   201 QLRIHKRAHTGEKPYKCN---------------------------QCDKAFLQNINLRIHKRAHT 238

  Fly   272 GEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAE 336
            ||.|:||..|.:.||:|..|.:|...|.|::|.:|:||...||.:|..|:|.|:||.|:.|||.:
Mouse   239 GEKPYKCNQCDKAFAQNGHLIIHKRTHTGEKPYECNQCGKAFADQSQLRIHRRIHTGEKPYKCNQ 303

  Fly   337 CSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSS 401
            |.|:|.:.|:|..|::.||||:|::|..|.|.|....:|::|...|.|||..:||.|.|.|....
Mouse   304 CDKAFAQHSNLRIHKRTHTGEKPYECNQCDKAFLQNINLKIHKRAHTGEKSYECSQCGKAFARYY 368

  Fly   402 QLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTH 466
            .|..|.:.||.:..::|..|.|.::.|.:|.:|.||||||.|:.|:.|.|.||.::..:.|.|||
Mouse   369 HLQCHERIHTEEKPYKCNQCDKVFSQSHSLQIHKRTHTGEKPYVCNQCGKAFADNSHLRRHKRTH 433

  Fly   467 TGEKPYKCSHCSTRYTQKSSLGRHLRRTLCGTK 499
            ||||||:|:.|.:.::|.|.|..| :||..|.|
Mouse   434 TGEKPYECNQCGSAFSQNSYLRIH-KRTHTGEK 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	156/408 (38%)
		C2H2 Zn finger	84..104	CDD:275368	5/19 (26%)
		C2H2 Zn finger	112..132	CDD:275368	4/22 (18%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	9/19 (47%)
		C2H2 Zn finger	223..243	CDD:275368	1/19 (5%)
		C2H2 Zn finger	250..270	CDD:275368	11/19 (58%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	9/19 (47%)
		C2H2 Zn finger	334..354	CDD:275368	7/19 (37%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)
Zfp933	NP_941021.1	KRAB	4..44	CDD:460171	5/29 (17%)
		C2H2 Zn finger	109..125	CDD:275368	4/17 (24%)
		C2H2 Zn finger	133..153	CDD:275368	8/19 (42%)
		COG5048	157..>467	CDD:227381	137/337 (41%)
		C2H2 Zn finger	161..181	CDD:275368	8/19 (42%)
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		C2H2 Zn finger	217..237	CDD:275368	12/46 (26%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
		C2H2 Zn finger	329..349	CDD:275368	6/19 (32%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	413..433	CDD:275368	7/19 (37%)
		C2H2 Zn finger	441..461	CDD:275368	7/20 (35%)