Protein Alignment CG5245 and Zfp94

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001186250.1
• Gene: Zfp94 / 22756
• MGIID: 107610
• Length: 486
• Species: Mus musculus
• Alignment Length: 503
• Identity: 153/503 - (30%)
• Similarity: 234/503 - (46%)
• Gaps: 87/503 - (17%)

  Fly    21 FEEELIFISNSDFEELESEIKIENF---CSYG----KDLEPVKGVPSKLKTCKSKIAKKRPLRKQ 78
            |.||.:.:.::...:|..::.:|||   .|.|    :::|.::.|..:..:.::....:...:..
Mouse    17 FSEEELGLLDAAQRKLYHDVMLENFRMLLSVGDKNPEEMESLEEVGLRHLSHEALFCSQIWQQVS 81

  Fly    79 TDTFKCTQC----QKTFTRKENLESH-----LRLHAEERPFECSHCSKSFGRRTHYKRHLLKH-- 132
            .|..|...|    ::|.:..:..::|     ...|:.::|:...||....|...:.:....|.
Mouse    82 RDLMKAGDCRVSIRETGSPLKRDDAHGADRKYSKHSGQKPWLQLHCGTDGGEEPYREERSEKDSW 146

  Fly   133 -------------EKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHL 184
                         ||| ::|..|...|.:.|.|:.|...||||:|:||.:|...|.|.|.|..|.
Mouse   147 DSPLQANGRPPAGEKR-YRCEKCDHAFCRLSGLQAHQVRHTGEKPYKCEECGKGFTRASTLLDHQ 210

  Fly   185 RTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTHAERSFK 249
            |.|:..:|::|..|.|:|.::|....|:|.|...:|:.|..|.|.|...|    |||.|.
Mouse   211 RGHTGNKPYQCHACWKSFCHSSEFNNHIRVHTGEKPYVCEECGKGFSQAS----HLLAHQ----- 266

  Fly   250 CTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFA 314
                              |.|.||.|:||..|.:.|:|:|.|.:|...|.|::|.||..|...|:
Mouse   267 ------------------RGHTGEKPYKCSTCGKGFSRSSDLNVHCRIHTGEKPYKCETCGKAFS 313

  Fly   315 MRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHM 379
            ..|:.:||.|:|:.::.|:||||.:.|..:|||..||:.||||||::|..|.:.| ||
Mouse   314 RVSILQVHQRVHSEDKPYQCAECGRGFTVESHLQAHQRSHTGERPYQCEECGRGF-CR------- 370

  Fly   380 LDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPF 444
                                :|..|.|...|||:..:.|..|.|.:...|.||.|.|.||||.|:
Mouse   371 --------------------ASNFLAHRGVHTGEKPYRCDICGKRFRQRSYLHDHHRIHTGEKPY 415

  Fly   445 KCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            ||..|.|:|:.|:..:.|.|.|||||||:|..|...::..|||..|.|
Mouse   416 KCEECGKVFSWSSYLKAHQRVHTGEKPYRCEECGKGFSWSSSLLIHQR 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	136/427 (32%)
		C2H2 Zn finger	84..104	CDD:275368	3/28 (11%)
		C2H2 Zn finger	112..132	CDD:275368	3/19 (16%)
		C2H2 Zn finger	139..159	CDD:275368	6/19 (32%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	7/19 (37%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	1/19 (5%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	10/19 (53%)
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		C2H2 Zn finger	390..410	CDD:275368	3/19 (16%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)
Zfp94	NP_001186250.1	KRAB	7..48	CDD:460171	8/30 (27%)
		C2H2 Zn finger	165..185	CDD:275368	6/19 (32%)
		zf-H2C2_2	178..202	CDD:463886	11/23 (48%)
		C2H2 Zn finger	193..213	CDD:275368	8/19 (42%)
		C2H2 Zn finger	221..241	CDD:275368	7/19 (37%)
		COG5048	<226..425	CDD:227381	86/253 (34%)
		C2H2 Zn finger	249..269	CDD:275368	10/46 (22%)
		C2H2 Zn finger	277..297	CDD:275368	7/19 (37%)
		C2H2 Zn finger	305..325	CDD:275368	7/19 (37%)
		C2H2 Zn finger	333..353	CDD:275368	10/19 (53%)
		C2H2 Zn finger	361..381	CDD:275368	8/47 (17%)
		C2H2 Zn finger	389..409	CDD:275368	8/19 (42%)
		C2H2 Zn finger	417..437	CDD:275368	7/19 (37%)
		zf-H2C2_2	429..453	CDD:463886	11/23 (48%)
		C2H2 Zn finger	445..465	CDD:275368	7/19 (37%)