Protein Alignment CG5245 and Zfp758

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001397432.1
• Gene: Zfp758 / 224598
• MGIID: 2385044
• Length: 646
• Species: Mus musculus
• Alignment Length: 533
• Identity: 185/533 - (34%)
• Similarity: 268/533 - (50%)
• Gaps: 63/533 - (11%)

  Fly    20 TFEEELIFISNSDFEELE-------SEIKIENF-----------CS-----YGKDLEPV--KGVP 59
            ||::..:..|..::|.|:       .::.:||:           |.     ..:|.:.:  :.:.
Mouse   109 TFKDVAVDFSQEEWECLDCAQRALYMDVMLENYNNLFFVENHYICHKYENFLDQDTQHIVHEDIN 173

  Fly    60 SKLKTCK-SKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEE--RPFECSHC---SKS 118
            .|||:.| .::||......|:..:| |..:.|.....||..|...:..|  :...|.:|   ..|
Mouse   174 IKLKSYKCHELAKIIYESSQSTPYK-TNLRDTSIESSNLNRHETGNTREPCKYKNCVNCLNLCSS 237

  Fly   119 FG-----------RRTHYKRHLL-----KHEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKC 167
            .|           ..|.|....|     |..|:.:|||...|.|.|...|:.|...||||:|:||
Mouse   238 IGLNQGIHIGKKDDETFYSNQNLMLKQTKSRKKHYKCSEYDKCFIQKGDLRSHQRMHTGEKPYKC 302

  Fly   168 TQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKL 232
            ::|:..|..||:|.:|.:.|:.::|:.|..|:|.|.|..:|:.|.|.|...:|:|||.|.|.|
Mouse   303 SECNKCFTLKSNLGIHQKIHTGKKPYRCFDCDKCFTNKYNLRTHQRIHSGEKPYKCSECDKCF-- 365

  Fly   233 RSILQK-HLLTH-----AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRL 291
               :|| .|:||     .|:.:||::|.|.|.....|:.|.|||.||.|:||..|.:.|.....|
Mouse   366 ---IQKFSLITHQRIHTGEKPYKCSECDKCFTNKSDLRGHQRVHTGEKPYKCSECDKCFTHKGSL 427

  Fly   292 QLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTG 356
            .:|...|:|::|.|||:|...|..:.....|.|:||.|:.||||||.|.|..:|.|..|:::|||
Mouse   428 SIHHRLHSGEKPYKCSECDKCFTQKCNLLTHQRIHTGEKPYKCAECDKCFTNRSDLRSHKKIHTG 492

  Fly   357 ERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHC 421
            |:|:||:.|.|.|..:..|.:|...|.|||..|||.|.|.|.....||:|.:.||.|..::|..|
Mouse   493 EKPYKCSECDKCFTHKFSLSIHQRLHSGEKPYKCSECDKCFTQKCNLLIHQRIHTEKKPYKCSEC 557

  Fly   422 SKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSS 486
            .|.:....:|.:|.|.||||.|:||:.|:|.|...::...|.|.||||||||||.|...:|.|.|
Mouse   558 DKCFIQKCSLLIHQRIHTGEKPYKCAECAKCFTDKSDLINHQRIHTGEKPYKCSECDKCFTHKCS 622

  Fly   487 L----GRHLRRTL 495
            |    |.|.|..|
Mouse   623 LSIHQGIHARAKL 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	161/430 (37%)
		C2H2 Zn finger	84..104	CDD:275368	5/19 (26%)
		C2H2 Zn finger	112..132	CDD:275368	7/38 (18%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	7/19 (37%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	8/20 (40%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	9/19 (47%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..492	CDD:275368	9/21 (43%)
Zfp758	NP_001397432.1	KRAB	107..147	CDD:460171	7/37 (19%)
		C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		COG5048	298..630	CDD:227381	138/336 (41%)
		C2H2 Zn finger	302..322	CDD:275368	7/19 (37%)
		C2H2 Zn finger	330..350	CDD:275368	8/19 (42%)
		C2H2 Zn finger	358..378	CDD:275368	10/24 (42%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		C2H2 Zn finger	414..434	CDD:275368	5/19 (26%)
		C2H2 Zn finger	442..462	CDD:275368	6/19 (32%)
		C2H2 Zn finger	470..490	CDD:275368	9/19 (47%)
		C2H2 Zn finger	498..518	CDD:275368	6/19 (32%)
		C2H2 Zn finger	526..546	CDD:275368	8/19 (42%)
		C2H2 Zn finger	554..574	CDD:275368	6/19 (32%)
		C2H2 Zn finger	582..602	CDD:275368	6/19 (32%)
		C2H2 Zn finger	610..630	CDD:275368	8/19 (42%)